3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 Olaparib Intermediate Factory
Kemurnian Tinggi, Produksi Komersial
Olaparib lan intermediet sing gegandhengan:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formilbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)metil)asam benzoat CAS 763114-26-7
1-(Cyclopropylcarbonyl) piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Jeneng Kimia | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
| sinonim | Dimetil 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate |
| Nomer CAS | 61260-15-9 |
| Nomer CAT | RF-PI453 |
| Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
| Formula Molekul | C10H11O5P |
| Bobot Molekul | 242.17 |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Bubuk Putih utawa Meh Putih |
| Kemurnian | ≥98,0% |
| Kelembapan (KF) | ≤0,50% |
| Total Impurities | ≤2,0% |
| Standar Tes | Standar Perusahaan |
| Panggunaan | Penengah Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), penengah saka Olaparib (CAS: 763113-22-0).Olaparib minangka jinis inhibitor polimerase ADP-ribose polimerase (PARP) novel, kalebu PARP1, PARP2, lan PARP3.PARP mediasi mekanisme ndandani DNA sing nduweni peran penting ing ndandani karusakan DNA lan apoptosis, mula olaparib khusus ngarahake mekanisme perbaikan DNA saka perbaikan DNA sel target lan njupuk efek kanthi nyerang kerentanan kritis sel kanker sing nggawa mutasi ing BRCA1 lan BRCA2.Amarga mekanisme iki, bisa digunakake kanggo terapi pangopènan pasien kanker ovarium berulang sing ngalami mutasi gen kerentanan kanker payudara (BRCA) uga sensitif marang obat platinum.
