4- [(1-Pyrrolidinylsulfonyl)metil]anilin CAS 334981-10-1 Kemurnian >99,0% (HPLC) Pabrik Prekursor Anilin Almotriptan
Pasokan Kimia Ruifu Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)metil]anilin CAS 334981-10-1
1-[(4-Nitrofenilmetil)sulfonil]pirolidin CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Jeneng Kimia | 4- [(1-Pyrrolidinylsulfonyl)metil]anilin |
sinonim | 1-[(4-Aminobenzyl)sulfonil]pirolidin;Almotriptan Aniline Prekursor |
Nomer CAS | 334981-10-1 |
Nomer CAT | RF-PI1948 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C11H16N2O2S |
Bobot Molekul | 240.32 |
Titik Lebur | 170,0 kanggo 176,0 ℃ |
Kapadhetan | 1.31 |
Kelarutan | Rada larut ing Toluene |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Kristal Putih nganti Samar |
Kemurnian / Metode Analisis | > 99,0% (HPLC) |
Mundhut ing Pangatusan | <0,50% |
Sisa ing Ignition | <0,50% |
Max Single Impurity | <0,50% |
Total Impurities | <1.00% |
Logam abot | <20 ppm |
Spektrum Infra Merah | Conforms kanggo Struktur |
NMR | Conforms kanggo Struktur |
Test Standar | Standar Perusahaan |
Panggunaan | Almotriptan Aniline Prekursor |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
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4- [(1-Pyrrolidinylsulfonyl)methyl]aniline (CAS: 334981-10-1) minangka perantara ing nyiapake Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Prekursor.Almotriptan Malate minangka obat triptan sing bisa digunakake kanggo perawatan migren.Almotriptan kalebu kategori obat agonis reseptor serotonin selektif.Almotriptan nduweni afinitas sing dhuwur lan spesifik kanggo reseptor serotonin 5-HT, sing luwih nyebabake vaskontriksi pembuluh getih otak lan mengaruhi redistribusi aliran getih.Efek kasebut nyegah sinyal nyeri saka dikirim menyang otak, lan luwih nyuda pelepasan zat alami tartamtu sing nyebabake nyeri, mual lan gejala migren liyane.Nanging, Almotriptan ora nyegah serangan migren.Almotriptan, dipasarake ing taun 2000, nduweni oralbioavailability paling dhuwur ing antarane kabeh triptan.Almotriptan dimetabolisme dening MAO-A lan CYP3A4, saengga duwe profil efek samping sing luwih apik yen dibandhingake karo Sumatriptan.