5-Bromo-2-Chloro-4′-Ethoxydiphenylmethane CAS 461432-23-5 Dapagliflozin Intermediate Factory
Pasokan Produsen, Kemurnian Tinggi, Produksi Komersial
Dapagliflozin (CAS: 461432-26-8) Perantara sing Gegandhengan:
5-Bromo-2-Asam Klorobenzoat CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Jeneng Kimia | 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane |
| sinonim | 4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)benzena;4-(5-Brom-2-Chlorbenzyl)fenil-Etileter;Dapagliflozin Bromo Impurity |
| Nomer CAS | 461432-23-5 |
| Nomer CAT | RF-PI447 |
| Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
| Formula Molekul | C15H14BrClO |
| Bobot Molekul | 325.63 |
| Titik Lebur | 41,0 kanggo 43,0 ℃ |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Putih nganti Pael Yellow Crystalline Powder |
| Kemurnian / Metode Analisis | ≥99,0% (HPLC) |
| Banyu (KF) | ≤0,50% |
| Total Impurities | ≤1,0% |
| Standar Tes | Standar Perusahaan |
| Panggunaan | Intermediate Dapagliflozin (CAS: 461432-26-8), diabetes tipe II |
Paket: Botol, tas Aluminium foil, Drum Karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)benzene (CAS: 461432-23-5) digunakake minangka perantara ing sintesis Dapagliflozin (CAS: 461432-26-8).Dapagliflozin minangka inhibitor glukosa cotransporter 2 (SGLT2) sing gumantung karo natrium ginjel selektif kanggo perawatan diabetes jinis 2.Dapagliflozin minangka obat antidiabetik anyar sing dikembangake bebarengan dening Bristol-Myers Squibb lan AstraZeneca, sing disetujoni dening European Medicines Agency (EMA) tanggal 12 November 2012. Ing tanggal 8 Januari 2014, US Food and Drug Administration (FDA) wis nyetujoni. Digunakake kanggo perawatan diabetes jinis II.
