Olaparib Intermediate CAS 763114-26-7 Kemurnian ≥98,5% Pabrik
Kemurnian Tinggi, Produksi Komersial
Olaparib lan intermediet sing gegandhengan:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formilbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)metil)asam benzoat CAS 763114-26-7
1-(Cyclopropylcarbonyl) piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Jeneng Kimia | 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)metil)asam benzoat |
| sinonim | 2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)metil]asam benzoat |
| Nomer CAS | 763114-26-7 |
| Nomer CAT | RF-PI450 |
| Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
| Formula Molekul | C16H11FN2O3 |
| Bobot Molekul | 298.27 |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Bubuk Kuning nganti Putih |
| Assay | ≥98,5% |
| Kelembapan (KF) | ≤0,50% |
| Total Impurities | ≤1,5% |
| Standar Tes | Standar Perusahaan |
| Panggunaan | Madya Olaparib (CAS: 763113-22-0) |
Paket: Botol, tas Aluminium foil, Drum Karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)metil)asam benzoat (CAS: 763114-26-7) minangka perantara sing digunakake ing sintesis Olaparib (CAS: 763113-22). -0).Olaparib, dipasarake dening AstraZeneca kanthi jeneng merek Lynparza, disetujoni ing AS ing Desember 2014 minangka terapi agen tunggal sing ditargetake kanggo perawatan kanker ovarium lanjut sing dimediasi BRCA. , fungsi minangka inhibitor polimerase ribosa poli ADP lan wis disetujoni khusus kanggo pasien sing wis nampa telu utawa luwih perawatan kemoterapi.Ing uji klinis, obat kasebut nambah kaslametan tanpa progresif kanggo pasien sing nandhang kanker ovarium serous sing sensitif platinum.Olaparib uga saiki ana ing macem-macem fase investigasi kanggo perawatan kanker paru-paru payudara, lambung, prostat, pankreas lan non-sel cilik.
