5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Intermediate Factory
Pasokan Produsen, Kemurnian Tinggi, Produksi Komersial
Dapagliflozin (CAS: 461432-26-8) Perantara sing Gegandhengan:
5-Bromo-2-Asam Klorobenzoat CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
Jeneng Kimia | 5-Bromo-2-Asam Klorobenzoat |
sinonim | 2-Chloro-5-Asam Bromobenzoat |
Nomer CAS | 21739-92-4 |
Nomer CAT | RF-PI439 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C7H4BrClO2 |
Bobot Molekul | 235.46 |
Titik Lebur | 154,0 nganti 156,0 ℃ (lit.) |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih nganti Kuning Cahya |
Assay | ≥99,0% |
Banyu (KF) | ≤0,50% |
Sisa ing Ignition | ≤0,30% |
2-Asam klorobenzoat | ≤0,30% |
2-Chloro-3-Asam Bromobenzoat | ≤0,30% |
Total Impurities | ≤1,0% |
Standar Tes | Standar Perusahaan |
Panggunaan | Intermediate Dapagliflozin (CAS: 461432-26-8), diabetes tipe II |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
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5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) digunakake minangka bahan wiwitan ing sintesis Dapagliflozin (CAS: 461432-26-8), inhibitor cotransporter-2 natrium-glukosa selektif sing nyuda ginjel. reabsorpsi glukosa lan digunakake kanggo nambani pasien diabetes tipe II.Dapagliflozin minangka inhibitor SGLT-2 (SLC5A2) sing kuat lan selektif kanthi EC50 1,1 nM.Nduwe permeabilitas sing apik ing membran sel Caco-2 lan minangka substrat kanggo P-glikoprotein (P-gp).Dapagliflozin disetujoni ing 2012 dening FDA.