5-Bromo-2-Chloropyrimidine CAS 32779-36-5 Purity ≥99,5% (HPLC) Macitentan Intermediate Factory
Produsen Pasokan Komersial Macitentan Related Intermediates
5-(4-Bromophenyl)-4,6-Dichloropyrimidine CAS 146533-41-7
5-Bromo-2-Chloropyrimidine CAS 32779-36-5
Jeneng Kimia | 5-Bromo-2-Chloropyrimidine |
sinonim | 2-Chloro-5-Bromopyrimidine;Macitentan Intermediate 5 |
Nomer CAS | 32779-36-5 |
Nomer CAT | RF-PI854 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C4H2BrClN2 |
Bobot Molekul | 193.43 |
Titik Lebur | 73,0 ~ 79,0 ℃ (lit.) |
Titik didih | 95 ℃ / 15 mmHg |
Kelarutan | Larut ing Metanol;Ora larut ing banyu |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih nganti Putih |
Identifikasi | IR/HPLC |
Kemurnian / Metode Analisis | ≥99,5% (HPLC) |
Kelembapan (KF) | ≤0,50% |
Sisa ing Ignition | ≤0,20% |
Impurity Tunggal | ≤0,30% |
Total Impurities | ≤0,50% |
Standar Tes | Standar Perusahaan |
Panggunaan | Penengah Farmasi;Macitentan Intermediate |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
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5-Bromo-2-Chloropyrimidine (CAS: 32779-36-5) ditrapake minangka perantara farmasi, ing sintesis Bahan Farmasi Aktif (API).Iki uga digunakake ing reaksi cross-coupling saka organologam indium karo 2,5-Dihalopyrimidines.5-Bromo-2-Chloropyrimidine minangka perantara Macitentan (CAS: 441798-33-0).Macitentan nampa persetujuan FDA AS ing Oktober 2013 kanggo perawatan hipertensi arteri paru (PAH) (kelompok WHO I) kanggo nundha perkembangan penyakit.