7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Kemurnian > 99,0% (HPLC) Afatinib Dimaleate Intermediate Factory

Katrangan singkat:

Jeneng: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Kemurnian: >99,0% (HPLC)

Penampilan: Werna kuning nganti coklat entheng

Penengah saka Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

Kirimi email kanggo kita

Detail Produk

Produk sing gegandhengan

Tag produk

katrangan:

Ruifu Chemical Supply Intermediates saka Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Asam Dietilphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-siji CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Sifat Kimia:

Jeneng Kimia	7-Chloro-6-Nitro-4-Hydroxyquinazoline
sinonim	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-siji;7-Chloro-6-Nitroquinazolin-4(3H)-siji
Nomer CAS	53449-14-2
Nomer CAT	RF-PI2030
Status Simpenan	Ing Simpenan, Skala Produksi Nganti Ton
Formula Molekul	C8H4ClN3O3
Bobot Molekul	225.59
Sensitivitas	Sensitif Panas
Kelarutan	Rada larut ing Dimethylformamide
Merk	Kimia Ruifu

Spesifikasi:

Item	Spesifikasi
Penampilan	Cahya kuning nganti coklat bubuk
Identifikasi (HPLC)	Wektu Penylametan Sampel Kudu Cocok karo Standar
Kemurnian / Metode Analisis	> 99,0% (HPLC)
Titik Lebur	300.0~303.0 ℃
Kandungan Air (KF)	<0,50%
Sisa ing Ignition	<0,30%
najis 1	<0,50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
najis 2	<0,50% (5,7-Dichloro-4[1H]quinazolinone)
najis 3	<1,00% (7-Chloro-8-Nitro-4[1H]kuinazolinon)
Impurity Tunggal liyane	<0,20%
Total Impurities	<1.00%
Logam Berat (Pb)	<20 ppm
Spektrum Infrared	Conforms kanggo Struktur
Proton NMR Spectrum	Proton NMR Spectrum
Test Standar	Standar Perusahaan
Panggunaan	Penengah saka Afatinib, Afatinib Dimaleate

Paket & Panyimpenan:

Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan

Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan

Kaluwihan:

FAQ:

Aplikasi:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) minangka perantara saka Afatinib Dimaleate (CAS: 850140-73-7).Afatinib minangka kulawarga blocker ErbB sing ora bisa dibatalake sing nyegah transmisi informasi lan ngalangi jalur utama sing ana ing pertumbuhan lan divisi sel kanker.Amarga mekanisme transduksi informasi kulawarga ErbB bisa dipicu dening pirang-pirang homodimer lan heterodimer, inhibisi simultan saka sawetara anggota kulawarga ErbB (kayata EGFR, HER2, ErbB3 lan ErbB4) bisa kanthi efektif ngganggu transduksi informasi hilir.Afatinib digunakake kanggo nambani jinis kanker paru-paru tartamtu (kanker paru-paru non-sel cilik) sing wis nyebar menyang bagean awak liyane.Iki kalebu kelas obat sing dikenal minangka inhibitor kinase.Kerjane kanthi alon utawa mungkasi wutah sel kanker.Iku ikatan karo protein tartamtu (reseptor epidermal-EGFR) ing sawetara tumor.