7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate Kemurnian Tinggi
Produsen Pasokan Irinotecan lan Intermediet sing gegandhengan:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Jeneng Kimia | 7-Ethyl-10-Hydroxycamptothecin |
sinonim | SN-38 |
Nomer CAS | 86639-52-3 |
Nomer CAT | RF-PI242 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C22H20N2O5 |
Bobot Molekul | 392.41 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Kristal Putih Kuning Muda |
Identifikasi (IR, UV) | (1) Spektrum panyerepan sinar ultraviolet selaras karo panjaluk (2) Spektrum penyerapan sinar inframerah sing cocog karo spektrum standar referensi kudu tundhuk karo tes sing disetujoni |
Titik Lebur | 228.0~235.0 ℃ |
Zat sing gegandhengan | ≤1,5% |
10-Hydroxycamptothecin | ≤0,30% |
7-Cthylcamptothecin | ≤0,70% |
Kotor sing ora dingerteni maksimal | ≤0,50% |
Mundhut ing Pangatusan | ≤1,0% |
Logam abot | ≤10ppm |
Sisa ing Ignition | ≤0,10% |
Kejelasan Solusi | Cetha |
Assay | ≥98,0% (HPLC) |
Standar Tes | Standar Perusahaan |
Panggunaan | Pharmaceutical Intermediate saka Irinotecan |
Paket: Botol, tas Aluminium foil, Drum karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
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Shanghai Ruifu Chemical Co., Ltd. minangka produsen lan supplier 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) kanthi kualitas dhuwur.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) minangka metabolit aktif saka inhibitor Topoisomerase I Irinotecan.SN-38 (NK012) nyegah sintesis DNA lan RNA karo IC50s saka 0,077 lan 1,3 μM, mungguh.7-Ethyl-10-Hydroxycamptothecin (SN-38), minangka metabolit aktif saka Irinotecan, turunan semisintetik saka camptothecin, sawijining alkaloid berbasis quinoline sing ditemokake ing kulit wit camptotheca Cina lan wit nothapodytes Asia.Sanajan 7-Ethyl-10-Hydroxycamptothecin nganti 1.000 kaping luwih kuat tinimbang Irinotecan, nanging durung diowahi dadi calon obat sing sregep amarga ora larut.Saiki lagi ngalami uji klinis kanthi kombinasi karo bagean liyane sing bisa uga bisa dadi efektif minangka obat antineoplastik.