7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0 Kemurnian >99,0% (HPLC) Aripiprazole Intermediate Factory
Produsen Pasokan Perantara Aripiprazole Kanthi Kemurnian Tinggi
Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl) piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Jeneng Kimia | 7-Hydroxy-3,4-Dihydro-2(1H)-Kuinolinon |
| sinonim | 3,4-Dihydro-7-Hydroxy-2(1H)-Kuinolinon;7-Hydroxy-3,4-Dihydrocarbostyril;7-Hydroxy-2-oxo-1,2,3,4-Tetrahydroquinoline;7-Hydroxycarbostyril;Aripiprazole Impurity 5;Aripiprazole EP Impurity A |
| Nomer CAS | 22246-18-0 |
| Nomer CAT | RF-PI1981 |
| Status Simpenan | Ing Simpenan, Kapasitas Produksi 60MT / Taun |
| Formula Molekul | C9H9NO2 |
| Bobot Molekul | 163.18 |
| Kelarutan | Larut ing Metanol |
| Kapadhetan | 1,282±0,060 g/cm3 |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Bubuk kuning utawa meh putih pucet |
| Kemurnian / Metode Analisis | >99,5% (HPLC, Persentase Area) |
| Titik Lebur | 229.0~235.0 ℃ |
| Mundhut ing Pangatusan | <0,50% |
| Kandungan Air (KF) | <0,50% |
| Pengotor Tunggal Maksimum | <0,30% |
| Total Impurities | <0,50% |
| Spektrum Infra Merah | Conforms kanggo Struktur |
| Test Standar | Standar Perusahaan |
| Panggunaan | Perantara Aripiprazole (CAS: 129722-12-9) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
Methyl 3-Bromobenzoate (CAS 618-89-3) bisa digunakake minangka prekursor Aripiprazole (CAS: 129722-12-9).Aripiprazole minangka jinis anyar saka turunan quinoline sing larut banget lipid, karakteristik efek farmakologis yaiku ora mung antagonis reseptor dopamin D 2 postsynaptic, nanging uga agonis reseptor dopamin D 2 presynaptic, uga bisa excite D 1, D 3, D 4 reseptor;Aripiprazole duweni efek ganda saka aktivasi parsial utawa antagonis reseptor ing reseptor 5-HT 1A;wis tumindak rampung antagonis ing reseptor 5-HT 2A.Fitur iki beda karo generasi pisanan, lan antipsikotik atipikal sing kalebu obat antipsikotik generasi kapindho, lan mulane diarani penstabil sistem dopamin utawa antipsikotik generasi katelu.Wiwit didol ing pasar, Aripiprazole utamane digunakake ing skizofrenia klinis, perawatan gangguan afektif lan gangguan kejiwaan liyane.Miturut literatur, aripiprazole duweni efek sing signifikan marang gejala skizofrenia positif lan negatif lan kuatir, depresi, fungsi kognitif, nalika luwih aman.Aripiprazoleuga dilapurake yen tamba uga bisa nambani kelainan mental liyane, kayata kelainan swasana ati episode manic, pikun digandhengake karo kelainan mental, kelainan kuatir, kelainan prilaku anak, depresi.
