7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Kemurnian >99,0% (GC) Agomelatine Intermediate
Produsen lan Supplier Utama Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
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| Jeneng Kimia | 7-Methoxy-1-Naphthaleneacetic Asam Etil Ester |
| sinonim | Etil 2-(7-Methoxynaphthalen-1-yl)asetat |
| Nomer CAS | 6836-21-1 |
| Nomer CAT | RF2687 |
| Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
| Formula Molekul | C15H16O3 |
| Bobot Molekul | 244.29 |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Cairan Transparan Kuning Cairan |
| Kemurnian / Metode Analisis | > 99,0% (GC) |
| Banyu (dening Karl Fischer) | <0,50% |
| Zat sing gegandhengan | <1.00% |
| Spektrum Infrared | Conforms kanggo Struktur |
| Spektrum NMR | Conforms kanggo Struktur |
| Test Standar | Standar Perusahaan |
| Panggunaan | Pharmaceutical Intermediate of Agomelatine (CAS: 138112-76-2) |
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7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) minangka perantara sintetik organik sing migunani, bisa digunakake minangka perantara farmasi Agomelatine (CAS: 138112-76-2).Agomelatine, sing dikembangake dening perusahaan Servier Prancis, minangka reseptor melatonin pisanan ing donya antidepresan MT1 lan MT2 agonis kelas.Iki ditrapake kanggo perawatan pasien diwasa kanthi depresi abot.Agomelatine minangka obat antidepresan.Agomelatine minangka agonis reseptor melatonin (MT) lan turunan melatonin.Iki ikatan karo reseptor MT1 lan MT2 (Kis = 0.14 lan 0.41 nM, masing-masing) lan duweni nilai EC50 0.1 nM ing tes ikatan [35S] GTPγS nggunakake sel CHO sing nuduhake reseptor MT2.Iki diklasifikasikake minangka disinhibitor norepinephrine-dopamine (NDDI) amarga antagonisme reseptor 5-HT2C.Aktivasi reseptor 5-HT2C dening serotonin nyegah pelepasan dopamin lan norepinefrin.
