Afatinib Dimaleate Intermediate CAS 314771-88-5 Kemurnian >99,0% (HPLC) Pabrik
Ruifu Chemical Supply Intermediates saka Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Asam Dietilphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-siji CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5
Jeneng Kimia | (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine |
sinonim | N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Afatinib Impurity |
Nomer CAS | 314771-88-5 |
Nomer CAT | RF-PI2027 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C18H14ClFN4O4 |
Bobot Molekul | 404.78 |
Kapadhetan | 1,534±0,060 g/cm3 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk kuning nganti kuning cahya |
Kemurnian / Metode Analisis | > 99,0% (HPLC) |
Mundhut ing Pangatusan | <0,50% |
Najis individu | <0,50% |
Total Impurities | <1.00% |
Logam abot | ≤20ppm |
Test Standar | Standar Perusahaan |
Panggunaan | Penengah saka Afatinib Dimaleate (CAS: 850140-73-7) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) digunakake ing preparation saka Afatinib Dimaleate (CAS: 850140-73-7).Afatinib minangka obat target anti-kanker inovatif, obat target oral generasi anyar, obat target anti-kanker pertama ing donya sing ora bisa dibatalake karo kulawarga ErbB, lan luwih efektif lan diangkah Ngalangi sinyal sing nyebabake pertumbuhan sel kanker. , ngurangi utawa nundha proliferasi sel kanker.Afatinib kalebu kelas obat sing dikenal minangka inhibitor tyrosine kinase.Kerjane kanthi ngalangi fungsi loro protein sing raket, yaiku reseptor faktor pertumbuhan epidermis (EGFR) lan reseptor faktor pertumbuhan epidermis manungsa 2 (HER2).Digunakake kanggo perawatan lini pertama pasien kanker paru-paru non-sel cilik metastatik.Afatinib minangka obat target anti-kanker inovatif, obat target oral generasi anyar, obat target anti-kanker pertama ing donya sing ora bisa dibatalake karo kulawarga ErbB, lan luwih efektif lan diangkah Ngalangi sinyal sing nyebabake pertumbuhan sel kanker. , ngurangi utawa nundha proliferasi sel kanker.