Aripiprazole Intermediate CAS 129722-34-5 Kemurnian >98,0% (HPLC)
Produsen Pasokan Perantara Aripiprazole Kanthi Kemurnian Tinggi
Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl) piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Jeneng Kimia | 7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Kuinolinon |
| sinonim | 7-(4-Bromobutoxy)-3,4-Dihydroquinolin-2(1H)-siji;7-(4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7-(4-Bromobutoxy)-2(1H)-Kuinolinon;Aripiprazole Impurity 3 |
| Nomer CAS | 129722-34-5 |
| Nomer CAT | RF-PI2269 |
| Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
| Formula Molekul | C13H16BrNO2 |
| Bobot Molekul | 298.18 |
| Kapadhetan | 1,383 g/cm3 |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Bubuk Kristal Putih utawa Kuning Pucat |
| Kemurnian / Metode Analisis | > 98,0% (HPLC) |
| Titik Lebur | 110.0~114.0 ℃ |
| Mundhut ing Pangatusan | <1.00% |
| Sisa ing Ignition | <0,50% |
| Logam Berat (Pb) | ≤20ppm |
| Proton NMR Spectrum | Conforms kanggo Struktur |
| Test Standar | Standar Perusahaan |
| Panggunaan | Perantara Aripiprazole (CAS: 129722-12-9) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone (CAS: 129722-34-5) minangka perantara ing sintesis Aripiprazole (CAS: 129722-12-9).Produk degradasi ing tablet Aripiprazole.Aripiprazole (Abilify).Paling anyar, longactingaripiprazole (turunan arylpiperazine quinolinone), katon minangka agonis parsial saka reseptor D2 (yaiku, ngrangsang reseptor D2 tartamtu nalika ngalangi wong liya gumantung saka lokasi ing otak lan konsentrasi obat kasebut).Bioavailabilitas Aripiprazole kira-kira 87%, kanthi konsentrasi plasma puncak tekan 3 nganti 5 jam sawise dosis.Iki dimetabolisme kanthi dehidrogenasi, hidroksilasi oksidatif, lan N-dealkilasi, umume ditengahi dening CYPs 3A4 lan 2D6 hepatik.Kanggo perawatan skizofrenia lan gangguan psikotik sing gegandhengan.Antagonis reseptor dopamin D2 sing selektif kanthi aktivitas agonis autoreseptor dopamin.Antipsikotik.
