Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Kemurnian ≥99,5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate

Katrangan singkat:

Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Fenyl)-Butyric Acid

CAS: 486460-00-8

Kemurnian: ≥99,5% (HPLC)

Penampilan: Bubuk Putih nganti Putih

Intermediate Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) kanggo perawatan diabetes mellitus jinis II

Kualitas Tinggi, Produksi Komersial

E-Mail: alvin@ruifuchem.com

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Detail Produk

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Tag produk

katrangan:

Pasokan Sitagliptin Phosphate Monohydrate Related Intermediate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Asam Trifluorofenilasetat CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3

Sifat Kimia:

Jeneng Kimia	Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Fenyl)-Butyric Acid
sinonim	(R)-Sitagliptin N-Boc-Acid Impurity
Nomer CAS	486460-00-8
Nomer CAT	RF-PI1192
Status Simpenan	Ing Simpenan, Skala Produksi Nganti Ton
Formula Molekul	C15H18F3NO4
Bobot Molekul	333.31
Titik Lebur	136,0 ~ 138,0 ℃
Merk	Kimia Ruifu

Spesifikasi:

Item	Spesifikasi
Penampilan	Bubuk Putih nganti Putih
Identifikasi dening HPLC	Wektu Retensi Sampel cocog karo Standar Referensi
Mundhut ing Pangatusan	≤0,50%
Awu sulfat	≤0,50%
Logam abot	<20 ppm
Isomer	≤0,50%
Zat sing gegandhengan
Najis A	≤0,50%
Sembarang Impurity Single Liyane	≤0,50%
Total Impurities	≤0,50%
Kemurnian	≥99,5% (HPLC)
Standar Tes	Standar Perusahaan
Panggunaan	Intermediate saka Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9)

Paket & Panyimpenan:

Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.

Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.

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Aplikasi:

Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) minangka perantara penting kanggo nyiapake sitagliptin.Sitagliptinphosphate minangka inhibitor dipeptidase -IV (DPP-4) pisanan sing disetujoni dening FDA ing taun 2006. Iki digunakake kanggo perawatan diabetes mellitus jinis II.Nduweni efek hypoglycemic sing jelas yen digunakake kanthi mandiri utawa digabungake karo metformin lan pioglitazone, lan aman kanggo njupuk, ditoleransi kanthi apik, kanthi efek samping sing sithik.Ing wulan Agustus 2009, obat kasebut disetujoni dening Uni Eropa minangka obat lini pertama kanggo perawatan diabetes tipe 2.Sawise 2011, siji-sijine negara wis nyetujoni kombinasi sitagliptin fosfat lan inhibitor alpha glycosidase utawa insulin.Sitagliptin fosfat minangka inhibitor dipeptidyl peptidase-IV pisanan sing disetujoni FDA sing digunakake ing perawatan diabetes jinis 2 nganti saiki, kanthi jeneng dagang Januvia.