Candesartan CAS 139481-59-7 Kemurnian >99,0% (HPLC) Pabrik
Pasokan Kimia Ruifu Candesartan Cilexetil Intermediate Kanthi Kemurnian Dhuwur
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0
Jeneng Kimia | Candesartan |
sinonim | CV-11974;2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]metil]-1H-Benzimidazole-7-Carboxylic Acid;3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]metil]-2-etoksi-3H-Benzimidazole-4-Asam Karboksilat;Candesartan M1;Candesartan Cilexetil EP Impurity G |
Nomer CAS | 139481-59-7 |
Nomer CAT | RF-PI1889 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C24H20N6O3 |
Bobot Molekul | 440.45 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih |
Identifikasi-HPLC | Wektu Penylametan Kaya Standar |
Identifikasi-IR | Mirip karo Standar |
Kemurnian / Metode Analisis | > 99,0% (HPLC) |
Titik Lebur | 183,0 ~ 185,0 ℃ |
Mundhut ing Pangatusan | <0,50% |
Kelembapan (KF) | <0,50% |
Sisa ing Ignition | <0,50% |
Logam abot | <20 ppm |
Najis individu | <1,00% (HPLC) |
Total Impurities | <1,00% (HPLC) |
Indeks bias | n20/D 1.745~1.747 |
Test Standar | Standar Perusahaan |
Panggunaan | API;Kanggo Perawatan Hipertensi |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
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Candesartan (CAS: 139481-59-7) minangka antagonis reseptor angiotensin II kanthi IC50 0,26 nM.Target: Angiotensin II Receptor candesartan dituduhake kanggo perawatan hipertensi.Candesartan Cilexetil pisanan disetujoni ing GB tanggal 29 Apr 1997, banjur disetujoni dening US Food and Drug Administration (FDA) tanggal 4 Juni 1998, lan disetujoni dening Pharmaceuticals and Medical Devices Agency of Japan (PMDA) tanggal 12 Mar 1999. Iki dikembangake dening AstraZeneca, banjur dipasarake minangka Atacand dening AstraZeneca ing GB lan AS, lan dipasarake minangka Blopress dening Takeda ing JP.Candesartan Cilexetil minangka blocker reseptor angiotensin II (ARB), mblokir vasoconstrictor lan efek sekresi aldosteron saka angiotensin II kanthi selektif mblokir ikatan angiotensin II menyang reseptor AT1 ing akeh jaringan, kayata otot polos pembuluh darah lan kelenjar adrenal.Atacand dituduhake kanggo perawatan hipertensi ing wong diwasa lan bocah umur 1 nganti <17 taun, gagal jantung (kelas NYHA II-IV) lan digunakake kanggo nyuda kematian kardiovaskular lan rawat inap gagal jantung.
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Candesartan CAS 139481-59-7 Kemurnian >99,0% (HPLC...
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Candesartan Cilexetil CAS 145040-37-5 Purity >9...
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1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83...
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Candesartan Cilexetil Intermediate CAS 139481-4...
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Candesartan Cilexetil Intermediate Eethyl Ester...
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Trityl Candesartan Cilexetil CAS 170791-09-0 Pu...
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