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Ibrutinib Intermediate CAS 330792-70-6 Kemurnian >98,0% (HPLC) Gambar Unggulan
  • Ibrutinib Intermediate CAS 330792-70-6 Kemurnian >98,0% (HPLC)

Ibrutinib Intermediate CAS 330792-70-6 Kemurnian >98,0% (HPLC)

Katrangan singkat:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Kemurnian: >98,0% (HPLC)

Penampilan: Putih-putih nganti bubuk kuning cahya

Penengah saka Ibrutinib (CAS: 936563-96-1) 

Kontak: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Detail Produk

Produk sing gegandhengan

Tag produk

Intermediet saka Ibrutinib:

Ibrutinib CAS 936563-96-1
3-Hydroxypiperidine CAS 6859-99-0
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Asam fenoksibenzoat CAS 2215-77-2
4-Asam Phenoxyphenylboronic CAS 51067-38-0
4-Aminopyrazolo [3,4-d] pirimidin CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pirimidin CAS 151266-23-8
Ibrutinib Deacrylylpiperidine CAS 330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Sifat Kimia:

Jeneng Kimia 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
sinonim Ibrutinib Intermediate N-3;3-Amino-5-(4-Phenoxyphenyl)pirasol-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pirazol;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Nomer CAS 330792-70-6
Status Simpenan Ing Simpenan, Skala Produksi Nganti Ton
Formula Molekul C16H12N4O
Bobot Molekul 276.29
Kapadhetan 1,37±0,10 g/cm3
COA & MSDS kasedhiya
asale Shanghai, China
Merk Kimia Ruifu

Spesifikasi:

Item Spesifikasi
Penampilan Bubuk Putih nganti Kuning Cahya
Kemurnian / Metode Analisis > 98,0% (HPLC)
Mundhut ing Pangatusan <1.00%
Sisa ing Ignition <0,50%
Total Impurities <2.00%
Logam Berat (Pb) <20 ppm
1 H NMR Spektrum Konsisten karo Struktur
Standar Tes Standar Perusahaan
Panggunaan Penengah saka Ibrutinib (CAS: 936563-96-1)

Paket & Panyimpenan:

Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.

Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.

Kaluwihan:

1

FAQ:

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330792-70-6 - Aplikasi:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) minangka perantara saka Ibrutinib (CAS: 936563-96-1).Ibrutinib nuduhake efek hambat sing kuat lan ora bisa dibatalake lan selektivitas kanggo aktivitas enzimatik Btk.Ing jalur sel DOHH2 sing diaktifake jalur BCR, Ibrutinib nyegah autofosforilasi Btk, fosforilasi substrat fisiologis Btk PLCγ, lan fosforilasi kinase hilir luwih lanjut, ERK kanthi IC50 saka 11 nM, 29 nM lan 13 nM, masing-masing.Ibrutinib nuduhake induksi sitotoksisitas sing gumantung karo dosis lan wektu sing signifikan ing sel leukemia limfositik kronis (CLL).Kajaba iku, Ibrutinib nyebabake pati sel gumantung saka aktivasi jalur caspase lan antagonizes kemampuan sel CLL kanggo proliferasi sawise sinyal TLR.

Tulis pesen sampeyan ing kene lan kirimake menyang kita