CAS 361440-67-7 Kemurnian >98,5% (HPLC) Pabrik
Ruifu Chemical Supply Related Intermediates
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(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]heksana-2-Asam Karboksilat tert-Butil Ester CAS 361440-67-7
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Jeneng Kimia | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]heksana-2-Asam Karboksilat tert-Butil Ester |
sinonim | N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]heksana-2-Carboxylate |
Nomer CAS | 361440-67-7 |
Nomer CAT | RF-PI1990 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C11H18N2O3 |
Bobot Molekul | 226.27 |
Titik didih | 388,9 ± 21,0 ℃ |
Kapadhetan | 1.228 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih |
Kemurnian / Metode Analisis | > 98,5% (HPLC) |
Mundhut ing Pangatusan | <0,50% |
Sisa ing Ignition | <0,20% |
Impurities individu | <1.00% |
Total Impurities | <1,50% |
Test Standar | Standar Perusahaan |
Panggunaan | Penengah API (CAS: 361442-04-8) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]heksana-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) minangka perantara API (CAS: 361442 -04-8).(CAS: 361442-04-8) minangka hypoglycemic oral (obat antidiabetes) saka kelas inhibitor dipeptidyl peptidase-4 (DPP-4).Pangembangan awal mung dening Bristol-Myers Squibb;ing 2007 AstraZeneca gabung karo Bristol-Myers Squibb kanggo ngembangaken senyawa final lan kolaborasi ing marketing saka tamba.Ing wulan Juni 2008, diumumake manawa Onglyza bakal dadi jeneng dagang sing bakal dipasarake.API (CAS: 361442-04-8) digunakake minangka monoterapi utawa ing kombinasi karo obat liya kanggo perawatan diabetes jinis 2.Diserep kanthi cepet sawise administrasi oral lan duwe profil farmakokinetik sing cocog karo dosis sapisan dina.Iki nduweni peran kanthi nyegah degradasi GLP-l.GLP-I minangka hormon sing diprodhuksi sacara alami ing usus sawise mangan.