Cisatracurium Besylate CAS 96946-42-8 Assay 95.0%~102.0% API Factory High Quality
Produsen kanthi Kemurnian Tinggi lan Kualitas Stabil
Jeneng Kimia: Cisatracurium Besylate
CAS: 96946-42-8
API Kualitas Tinggi, Produksi Komersial
Jeneng Kimia | Cisatracurium Besylate |
Nomer CAS | 96946-42-8 |
Nomer CAT | RF-API13 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C53H72N2O12.2C6H5O3S |
Bobot Molekul | 1243.49 |
Titik Lebur | 90.0~93.0 ℃ |
Kondisi Pengiriman | Ing Suhu Sekitar |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Wêdakakêna putih utawa meh putih, ora ana ambune, rada higroskopis |
Kelarutan | Bebas larut ing diklorometana, asetonitril, rada larut ing banyu |
Rotasi spesifik | -35,0° nganti -45,0° (C=10mg/ml, 0,1mg/ml asam benzena sulfonat) |
Identifikasi | Larut karo asam hidrokorat encer, bismut encer kalium iodida TS, udan kuning bakal diprodhuksi |
Identifikasi | 1. HPLC ;2. IR |
Assay | 95.0~102.0% (C65H82N2O18S2 ing basis garing) |
pH | 3,5 kanggo 5,0 |
Kajelasan & Werna Solusi | Kudu Clear & Colorless |
Mundhut ing Pangatusan | ≤2,0% |
Sisa ing Ignition | ≤0,20% |
Logam abot | ≤20ppm |
Isomer Trans-Trans | ≤0,50% |
Isomer Cis-Trans | ≤0,50% |
Mono-quaternaries | ≤1,50% |
Sembarang Najis Individu | ≤1,50% |
Total Impurities | ≤5,0% |
Isomer Optik SS-Isomer | ≤1,50% |
Isomer Optik RS- Isomer | ≤1,00% |
Sulfat | ≤50ppm |
Etil | ≤0,50% |
Aseton | ≤0,50% |
Metanol | ≤0,3% |
Diklorometana | ≤0,06% |
asetonitril | ≤0,041% |
Metilbenzena | ≤0,089% |
Sisa Solvents Acetonitrile | ≤410ppm |
Test Standar | Farmakope Cina (CP) |
Panggunaan | Active Pharmaceutical Ingredient (API) |
Paket: Botol, tas Aluminium foil, Drum karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
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Cisatracurium Besylate (CAS 96946-42-8) yaiku wangun uyah benzena sulfonat saka atracurium.Iki minangka obat pelumpuh otot non-depolarisasi sintetik kanthi peran sing padha karo tubocurarine.Dosis perawatan ora mengaruhi fungsi jantung, ati lan ginjel.Uga ora duwe properti akumulasi.Uga bisa nyebabake pelepasan histamin nalika digunakake ing dosis gedhe.Kanggo istirahat otot utawa kontrol ambegan sing dibutuhake ing operasi, dibandhingake karo obat anestesi otot santai utama klinis saiki, cisatracurium besylate ora dimetabolisme liwat ati utawa ginjel, lan nduweni stabilitas kardiovaskular;efek relaksasi otot 3 kaping luwih kuat tinimbang atracurium tanpa efek samping kardiovaskular.Cisatracurium besylate utamane ditrapake kanggo anestesi umum, lan bisa digunakake kanthi akeh ing intubasi, ngobati disfungsi ati lan ginjel, digunakake ing operasi jantung lan pasien tuwa lan bocah.Dibandhingake karo atracurium, produk iki ora duwe efek saleh gumantung dosis saka release histamin;Nanging, kerugian kasebut yaiku pasien sing nandhang gangguan fungsi ati lan ginjel kudu ditindakake kanthi ati-ati.Wiwit 1996 kanggo pisanan nalika obat iki mlebu ing pasar ing Inggris, negara manca wis mboko sithik Applied kanggo ngganti vecuronium lan atracurium minangka utama relaxants otot Clinical.
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