Cyano-Irbesartan CAS 138401-24-8 Kemurnian >98,0% (HPLC) Pabrik Intermediate Irbesartan
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Jeneng Kimia | Cyano-Irbesartan |
sinonim | CyanoIrbesartan;Irbesartan Cyano Impurity;Hidrokarbon Irbesartan;Irbesartan Impurity 6;2-Butil-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]metil]-1,3-diazaspiro[4,4]non-1-en-4-siji;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)metil]-[1,1'-biphenyl]-2-karbonitril |
Nomer CAS | 138401-24-8 |
Nomer CAT | RF-PI1892 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C25H27N3O |
Bobot Molekul | 385.51 |
Kapadhetan | 1.15 |
Kelarutan (Soluble in) | Metanol |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Putih nganti meh putih bubuk nganti kristal |
Kemurnian / Metode Analisis | > 98,0% (HPLC) |
Kemurnian | > 97,0% (Kanthi Total Nitrogen) |
Titik Lebur | 91,0 kanggo 95,0 ℃ |
Mundhut ing Pangatusan | <1.00% |
Impurity Tunggal | <1.00% |
Logam abot | <20 ppm |
Spektrum Infra Merah | Conforms kanggo Struktur |
Test Standar | Standar Perusahaan |
Panggunaan | Intermediate / Impurity of Irbesartan (CAS: 138402-11-6) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
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Cyano-Irbesartan (CAS: 138401-24-8) minangka penengah utawa najis saka Irbesartan (CAS: 138402-11-6).Irbesartan minangka inhibitor reseptor angiotensin II (Angiotensin II, Ang II).Reseptor angiotensin II dipérang dadi rong jinis: AT1 lan AT2.Irbesartan kanthi selektif ngalangi reseptor AT1 Angli.Bisa nyandhet konversi Ang dadi Ang, khusus bisa nglawan reseptor enzim 1 sing ngowahi angiotensin (AT1).Efek antagonis ing AT1 8500 kaping luwih saka AT2.Bisa selektif mblokir ikatan saka reseptor Ang lan AT1 liwat Nyandhet vasoconstriction lan release saka aldosteron, asil ing efek hypotensive.Produk iki ora nyandhet angiotensin converting enzyme (ACE), renin, reseptor hormon liyane, uga ora nyandhet saluran ion sing ana hubungane karo regulasi tekanan getih lan keseimbangan sodium.Irbesartan uga bisa nyuda remodeling listrik miokardium, saengga bisa nyuda tingkat kematian pasien hipertensi.Saiki minangka obat sing paling efektif kanggo perawatan hipertensi lan penyakit kardiovaskular.
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