Darunavir CAS 206361-99-1 Anti-HIV Purity ≥99.0% API High Purity HIV Protease Inhibitor
Pasokan ProdusenProduk terkait Darunavir:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
Jeneng Kimia | Darunavir |
sinonim | TMC114;UIC-94017 |
Nomer CAS | 206361-99-1 |
Nomer CAT | RF-API68 |
Status Simpenan | Ing Stok, Skala Produksi Nganti Atusan Kilogram |
Formula Molekul | C27H37N3O7S |
Bobot Molekul | 547.66 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Kristal Putih utawa Off-White |
Identifikasi | MS/HNMR HPLC |
Kelarutan | Larut ing DMSO, rada larut ing banyu |
Titik Lebur | 74,0 ~ 76,0 ℃ |
Identifikasi | 1H NMR |
Kemurnian / Metode Analisis | ≥99,0% (HPLC) |
Zat sing gegandhengan | |
Max Single Impurity | ≤0,30% |
Total Impurities | ≤1,0% |
Sisa Solvents | Etanol ≤0,30% |
Mundhut ing Pangatusan | ≤0,50% |
Sisa ing Ignition | ≤0,10% |
Logam abot | ≤20ppm |
Arsenik | ≤1.5ppm |
Test Standar | Standar Perusahaan |
Panggunaan | Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor Anti-HIV |
Paket: Botol, tas Aluminium foil, Drum Karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
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Darunavir (jeneng merek Prezista, biyen dikenal minangka TMC114) minangka obat inhibitor protease sing digunakake kanggo nambani infeksi HIV.Darunavir minangka pilihan perawatan sing disaranake OARAC kanggo wong diwasa lan remaja sing naif lan ngalami perawatan.Darunavir minangka inhibitor protease anti retroviral non-peptida anyar ing terapi AIDS.Iki pisanan dikembangake dening cabang Iceland pharmaceutical Johnson, Tibotec.Iki minangka bioavailabilitas paling dhuwur ing 6 inhibitor protease (saquinavir, ritonavirvir, indinavir, naftalena nelfinavir, amprenavir lan ABT378/r).Tumindak kanthi ngalangi pembentukan partikel virus anyar lan diwasa saka permukaan sel inang sing kena infeksi lan nyegah protease virus.Nalika prodhuk digunakake kanggo dangu, iku biasane bisa ngurangi vektor virus HIV ing getih, nambah jumlah sel CD4, nyuda kasempatan saka infèksi HIV, nambah kualitas urip lan ndawakake umur.Cocog kanggo wong diwasa sing kena infeksi virus HIV nanging ora duwe pengaruh marang panggunaan obat antiretroviral sing ana.Obat kasebut kudu digabungake karo panggunaan ritonavir dosis rendah utawa agen antiretroviral liyane, supaya bisa nambah efektifitas.Aktivitas antivirus in vitro bisa dievaluasi kanthi nglawan limfosit lan limfosit sing kena infeksi akut lan kronis ing getih perifer.