Asam Dietilphosphonoacetic CAS 3095-95-2 Kemurnian > 99,5% (HPLC) Afatinib Dimaleate Intermediate Factory
Ruifu Chemical Supply Intermediates saka Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Asam Dietilphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-siji CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5
Jeneng Kimia | Asam Dietilphosphonoacetic |
sinonim | 2- (Diethoxyphosphoryl)Asam asetat;(Diethoxyphosphinyl)asam asetat;Dietil Carboxymethylphosphonate;NSC 272281 |
Nomer CAS | 3095-95-2 |
Nomer CAT | RF-PI2024 |
Status Simpenan | Ing Simpenan, Kapasitas Produksi 30MT / Wulan |
Formula Molekul | (C2H5O)2P(O)CH2CO2H |
Bobot Molekul | 196.14 |
Titik didih | 150 ℃ / 0,05 mmHg (lit.) |
Kapadhetan | 1,220 g/mL ing 25 ℃ (lit.) |
Indeks bias | n20/D 1,445 (lit.) |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Cairan Tanpa Warna |
Identifikasi (HPLC) | Wektu retensi puncak utama sing dipikolehi saka sampel yaiku ing 5% saka sampel referensi. |
Kemurnian / Metode Analisis | > 99,5% (HPLC) |
Spektrum Infrared | Conforms kanggo Struktur |
Proton NMR Spectrum | Conforms kanggo Struktur |
Kelembapan (KF) | <0,50% |
Total Impurities | <0,50% |
Test Standar | Standar Perusahaan |
Panggunaan | Penengah saka Afatinib Dimaleate (CAS: 850140-73-7) |
Paket: Botol Fluorinated, 25kg / Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
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Diethylphosphonoacetic Acid (CAS: 3095-95-2), Tumindak minangka nukleofil kanggo reaksi tambahan nukleofilik kanggo sintesis epoksida allene Reaktan kanggo: Studi stereoselektifitas reaksi Staudinger;Pembentukan enantioselektif diol liwat reaksi epoksidasi lan hidrasi;reaksi Horner-Wadsworth-Emmons;Chelation remot kontrol rearrangement Ireland-Claisen;Reaksi Ugi-Dieckmann kanggo sintesis turunan asam tetramat;Digunakake kanggo nggawe intermediet fosfonoester kanggo reaksi HEW intramolekul.Asam Dietilphosphonoacetic minangka perantara saka Afatinib Dimaleate (CAS: 850140-73-7).Afatinib Dimaleate disetujoni dening US Food and Drug Administration (FDA) ing 2013 kanggo perawatan kanker paru-paru sel non-cilik (NSCLC).Khusus, disetujoni kanggo pasien sing ngalami tumor NSCLC metastatik sing ngemot penghapusan ekson reseptor faktor pertumbuhan epidermal (EGFR) utawa mutasi exon 21.Afatinib Dimaleate minangka inhibitor kovalen saka ErbB tyrosine kinase (tyk), sing nyuda sinyal ErbB kanthi ikatan sing ora bisa dibatalake saka situs pengikat EGFR tyk.
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Asam Dietilphosphonoacetic CAS 3095-95-2 Purit...
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