LCZ696 Intermediate CAS 1426129-50-1 Kemurnian ≥98,0% (HPLC) ee ≥99,0% Kemurnian Tinggi Pabrik
Pasokan Komersial LCZ696 (CAS: 936623-90-4) Perantara sing Gegandhengan:
(R)-tert-Butyl (1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate CAS: 1426129-50-1
(R,E)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S)-5-(1,1'-bifenil-4-yl)-4-((tert-butoxycarbonyl)amino)-2-asam metilpentanoat CAS: 1012341-50-2
(2R,4S)-etil 5-(1,1'-biphenyl-4-yl)-4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (garam hemikalsium) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
LCZ696;Entresto;Campuran Sacubitril karo Valsartan CAS: 936623-90-4
| Jeneng Kimia | (R)-tert-Butil (1-([1,1-bifenil]-4-yl)-3-hidroksipropan-2-yl)karbamat |
| sinonim | LCZ696 Penengah |
| Nomer CAS | 1426129-50-1 |
| Nomer CAT | RF-PI169 |
| Status Simpenan | Ing Stok, Skala Produksi Nganti Atusan Kilogram |
| Formula Molekul | C20H25NO3 |
| Bobot Molekul | 327.42 |
| Merk | Kimia Ruifu |
| Item | Spesifikasi |
| Penampilan | Bubuk Putih nganti Putih |
| Kemurnian / Metode Analisis | ≥98,0% (HPLC) |
| Enantiomeric Excess | ee: ≥99,0% |
| Kelembapan (KF) | ≤1,0% |
| Bahan sing gegandhengan A | ≤1,0% (RRT=0,5) A=(R)-3-([1,1'-biphenyl]-4-yl)-2-aminopropan-1-ol |
| Bahan sing Gegandhengan B | ≤1,0% (RRT=0,85) B=Trifenilfosfin oksida |
| Zat liyane | ≤1,0% |
| Total Impurities | ≤2,0% |
| Standar Tes | Standar Perusahaan |
| Panggunaan | Penengah LCZ696 (CAS: 936623-90-4) ing perawatan HFrEF |
Paket: Botol, tas Aluminium foil, Drum karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
Produsen kanthi Kemurnian Tinggi lan Kualitas Stabil
Pasokan Komersial LCZ696 (CAS: 936623-90-4) Perantara sing Gegandhengan:
(R)-tert-Butyl (1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate CAS: 1426129-50-1
(R,E)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S)-5-(1,1'-bifenil-4-yl)-4-((tert-butoxycarbonyl)amino)-2-asam metilpentanoat CAS: 1012341-50-2
(2R,4S)-etil 5-(1,1'-biphenyl-4-yl)-4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (garam hemikalsium) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
LCZ696;Entresto;Campuran Sacubitril karo Valsartan CAS: 936623-90-4
LCZ696 minangka obat eksperimen sing dikembangake dening Novartis Pharmaceutical saka Amerika Serikat kanggo perawatan pasien Gagal Jantung kanthi Fraksi Ejeksi Suda (HFrEF).Gagal jantung minangka penyakit sing ngancam nyawa.Jantung pasien ora bisa ngompa getih sing cukup kanggo nyuplai awak, lan katon gejala dyspnea, lemes lan retensi cairan alon-alon, banjur saya tambah akeh, kanthi signifikan mengaruhi kualitas urip.LCZ696 bisa ningkatake pertahanan alami awak marang gagal jantung, uga nambah tingkat peptida natriuretik lan peptida vasoaktif endogen liyane, lan nyandhet sistem renin-angiotensin-aldosteron (RAAS).LCZ696 wis digabungake karo Obat Hipertensi Novartis (Diovan, jeneng umum: valsartan) lan obat eksperimental AHU-377.AHU377 ngalangi mekanisme loro peptida sing tanggung jawab kanggo nyuda tekanan getih.Diovan mbenakake vasodilatasi lan stimulates awak kanggo excrete sodium lan banyu.
