Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~102.0% Gambar Unggulan Pabrik

Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~102.0% Pabrik

Katrangan singkat:

Jeneng Kimia: Lenvatinib Mesylate

CAS: 857890-39-2

Assay: 98,0 ~ 102,0%

Penampilan: Putih nganti Bubuk Putih utawa Kristal

Kontak: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Kirimi email kanggo kita

Detail Produk

Produk sing gegandhengan

Tag produk

katrangan:

Pasokan Kimia Ruifu Lenvatinib Mesylate Intermediates Kanthi Kemurnian Dhuwur
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Metil 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Metil 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimetil-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Sifat Kimia:

Jeneng Kimia	Lenvatinib Mesylate
sinonim	4-[3-Chloro-4-[(cyclopropylaminocarbonyl)amino]phenoxy]-7-Methoxy-6-Quinolinecarboxamide Mesylate;E 7080 Mesylate;Lenvima
Nomer CAS	857890-39-2
Nomer CAT	RF-PI1975
Status Simpenan	Ing Simpenan, Skala Produksi Nganti Ton
Formula Molekul	C21H19N4O4Cl.CH4O3S
Bobot Molekul	522.96
Merk	Kimia Ruifu

Spesifikasi:

Item	Spesifikasi
Penampilan	Putih nganti Bubuk Putih utawa Kristal
Identifikasi	Miturut IR;Miturut UV;Miturut HPLC
Kelarutan	Rada larut ing banyu, Praktis ora larut ing etanol
Titik Lebur	228.0~230.0 ℃
Kandungan Air (KF)	<1.00%
Sisa ing Ignition	<0,10%
Logam abot	<20 ppm
Zat sing gegandhengan
Sembarang Impurity Single	<0,50%
Total Impurities	<1.00%
Metode Assay/Analisis	98.0~102.0% (Basis HPLC ing Pangeringan)
Akeh Kapadhetan	0,40gm/ml~0,60gm/ml
Test Standar	Standar Perusahaan
Panggunaan	API

Paket & Panyimpenan:

Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan

Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan

Kaluwihan:

FAQ:

Aplikasi:

Lenvatinib Mesylate (CAS: 857890-39-2) minangka inhibitor lisan lan multi-target VEGFR1-3, FGFR1-4, PDGFR, KIT, lan RET, kanthi aktivitas antitumor sing kuat.Lenvatinib Mesylate minangka inhibitor tirosin kinase (RTK) reseptor sing nduweni selektivitas kanggo VEGFR2.Iku nuduhake aktivitas antineoplastik, lan wis dituduhake kanggo perawatan saka patients karo ambalan lokal utawa metastatik, progresif, radioaktif yodium (RAI) -refractory dibedakake kanker tiroid.Lenvatinib Mesylate pisanan disetujoni dening US Food and Drug Administration (FDA) ing Feb 13, 2015, banjur disetujoni dening Pharmaceuticals and Medical Devices Agency of Japan (PMDA) ing Mar 26, 2015, lan disetujoni dening European Medicine Agency (EMA) ing 28 Mei 2015. Iki dikembangake lan dipasarake minangka Lenvima® dening Eisai.Lenvatinib Mesylate minangka inhibitor tirosin kinase reseptor macem-macem lisan kanthi mode pengikatan unik sing selektif nyegah aktivitas kinase saka reseptor faktor pertumbuhan endothelial vaskular (VEGF), saliyane kinase tirosin sing ana hubungane karo proangiogenik lan onkogenik sing diduga melu proliferasi tumor. .Iki dituduhake kanggo perawatan kanker tiroid sing dibedakake radioiodine-refractory progresif.Lenvimadigunakake dhewe kanggo nambani kanker tiroid sing dibedakake (DTC), jinis kanker tiroid sing ora bisa diobati maneh karo yodium radioaktif lan terus maju.LENVIMA digunakake bebarengan karo obat liya sing diarani everolimus kanggo nambani wong diwasa kanthi jinis kanker ginjel sing diarani karsinoma sel ginjel lanjut (RCC) sawise siji perawatan karo obat anti-kanker liyane.