Lenvatinib Mesylate Intermediate CAS 15568-85-1 Kemurnian >97,0% (HPLC) Gambar Unggulan Pabrik

Lenvatinib Mesylate Intermediate CAS 15568-85-1 Kemurnian >97,0% (HPLC) Pabrik

Katrangan singkat:

5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione

CAS: 15568-85-1

Kemurnian: >97,0% (HPLC)

Penampilan: Bubuk kuning

Penengah saka Lenvatinib Mesylate CAS 857890-39-2

Kontak: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Kirimi email kanggo kita

Detail Produk

Produk sing gegandhengan

Tag produk

katrangan:

Pasokan Kimia Ruifu Lenvatinib Mesylate Intermediates Kanthi Kemurnian Dhuwur
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Metil 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Metil 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimetil-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Sifat Kimia:

Jeneng Kimia	5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione
sinonim	5-(Methoxymethylene) Asam Meldrum;Cabozantinib Impurity 56;Pengotor Lenvatinib 79
Nomer CAS	15568-85-1
Nomer CAT	RF-PI1967
Status Simpenan	Ing Simpenan, Skala Produksi Nganti Ton
Formula Molekul	C8H10O5
Bobot Molekul	186.16
Titik Lebur	132.0~134.0 ℃
Kapadhetan	1,297±0,06 g/cm3
Merk	Kimia Ruifu

Spesifikasi:

Item	Spesifikasi
Penampilan	Bubuk Kuning
1 H NMR Spektrum	Konsisten karo Struktur
Kemurnian / Metode Analisis	> 97,0% (HPLC)
Total Impurities	<3.00%
Test Standar	Standar Perusahaan
Panggunaan	Penengah saka Lenvatinib Mesylate (CAS: 857890-39-2)

Paket & Panyimpenan:

Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan

Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan

Kaluwihan:

FAQ:

Aplikasi:

5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS:15568-85-1) minangka perantara saka Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib minangka obat kanker tiroid sing dikembangake dening Eisai Corporation of Japan (Kode: E7080), sing kalebu inhibitor multi-reseptor tyrosine kinase (RTK) lisan lan bisa nyandhet aktivitas kinase saka faktor pertumbuhan endothelial vaskular (VEGF) Reseptor VEGFR1 ( FLT1), VEGFR2 (KDR), lan VEGFR3 (FLT4).Lenvatinib uga bisa nyandhet keterlibatan RTK liyane ing angiogenesis patologis, pertumbuhan tumor, lan perkembangan kanker kajaba fungsi seluler normal kalebu reseptor faktor pertumbuhan fibroblast (FGF) FGFR1, 2, 3, lan 4;platelet-derived growth factor receptor (PDGFR [alpha]), KIT, lan RET.[Indikasi]: Lenvatinib cocok kanggo perawatan pasien kanker tiroid saka jinis kambuh utawa metastasis lokal, jinis progresif lan jinis diferensiasi yodium-refraktori radioaktif.Tanggal 13 Februari 2015, FDA AS nyetujoni obat antikanker Lenvatinib kanggo perawatan kanker tiroid.Lenvatinib minangka inhibitor enzim multi-target, sing bisa nyandhet VEGFR2 lan VEGFR3 (reseptor faktor pertumbuhan endothelial vaskular).Jeneng dagang Lenvatinib yaiku Lenvima.Ing Mei 20, 2015, European Medicines Agency (EMA) nyetujoni Lenvatinib kanggo perawatan kanker tiroid (DTC) invasif, maju sacara lokal utawa metastatik (papillary, follicular, Hurthle type).Ing uji coba, wektu urip rata-rata kanggo pasien DTC radioaktif yodium-refractory sing diobati karo Lenvatinib yaiku 18 sasi, dene nilai kanggo pasien sing njupuk plasebo mung 3 wulan.