Palbociclib Intermediate CAS 1016636-76-2 Kemurnian >99,0% (HPLC) Pabrik
Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butil 4-(6-Nitropyridin-3-yl)piperazin-1-Karboksilat CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pirimidin-7(8H)-siji CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pirimidin-7-siji CAS 1013916-37-4
Jeneng Kimia | 6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pirimidin-7(8H)-siji |
sinonim | Palbociclib-Pb3 |
Nomer CAS | 1016636-76-2 |
Nomer CAT | RF-PI1849 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C13H13BrClN3O |
Bobot Molekul | 342.63 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk putih nganti kuning cahya |
Kemurnian / Metode Analisis | > 99,0% (HPLC) |
Zat sing gegandhengan | <1.00% |
Mundhut ing Pangatusan | <0,50% |
Banyu (KF) | <0,50% |
Test Standar | Standar Perusahaan |
Panggunaan | Penengah Palbociclib (CAS: 571190-30-2) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (CAS: 1016636-76-2) minangka perantara saka Palbociclib (CAS: 571190- 30-2).Palbociclib minangka obat kanggo perawatan kanker payudara ER-positif lan HER2-negatif sing dikembangake.Palbociclib minangka inhibitor selektif saka kinase sing gumantung karo cyclin CDK4 lan CDK6.Tanggal 3 Februari 2015, FDA AS nyetujoni Pfizer's Palbociclib (jeneng dagang: Ibrance) kanggo perawatan kanker payudara lanjut/metastatik ing wanita postmenopause.Palbociclib minangka inhibitor CDK4/6 pisanan sing nampa persetujuan FDA.