Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
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Jeneng Kimia | 2-Etilbutil ((S)-(perfluorofenoksi)(fenoksi)fosforil)-L-alaninat |
sinonim | N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-etilbutil ester;Remdesivir Intermediate;Remdesivir-001;Remdesivir Impurity 21 |
Nomer CAS | 1911578-98-7 |
Nomer CAT | RF-PI303 |
Status Simpenan | Ing Stok, Skala Produksi Nganti Atusan Kilogram |
Formula Molekul | C21H27N2O7P |
Bobot Molekul | 495.38 |
Kapadhetan | 1,2 g/cm3 |
Titik Lebur | 92,0 ~ 96,0 ℃ (lit.) |
Titik didih | 356,7 ℃ ing 760 mmHg |
Kondisi Pengiriman | Dikirim Ing Suhu Sekitar |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih nganti Putih |
Spektrum Infrared | Conforms kanggo Struktur |
Kemurnian | ≥99,0% |
Mundhut ing Pangatusan | ≤0,50% |
Impurity Tunggal | ≤0,50% |
Total Impurities | ≤1,0% |
Logam abot | ≤20ppm |
Test Standar | Standar Perusahaan |
Panggunaan | Perantara Remdesivir (CAS 1809249-37-3) |
Paket: Botol, tas Aluminium foil, Drum karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) minangka perantara kunci lanjutan ing nyiapake analog sing gegandhengan karo Remdesivir.Remdesivir minangka prodrug monophosphoramidate saka analog adenosin, minangka agen antivirus spektrum luas sing diselidiki kanthi aktivitas in vitro nglawan SARS coronavirus, MERS coronavirus lan, luwih anyar, Covid-19.Remdesivir utamane dikembangake minangka perawatan kanggo infeksi filovirus kayata penyakit virus Ebola utawa virus Marburg.Sabanjure, Remdesivir ditemokake nuduhake aktivitas antivirus marang virus RNA untai tunggal liyane kayata virus respiratory syncytial, virus Nipah, virus Hendra, virus Junin, virus demam Lassa lan coronaviruses (kalebu virus MERS lan SARS).Bubar iki lagi diteliti minangka obat sing njanjeni kanggo perawatan COVID-19 (virus jinis SARS anyar).Remdesivir, sing dikembangake dening Gilead Sciences, minangka prodrug adenosin sing metabolisasi dadi bentuk aktif GS-441524 sing ngganggu tumindak polimerase RNA sing gumantung karo RNA virus lan nyingkiri proofreading dening virus exoribonuclease (ExoN), nyebabake nyuda produksi RNA virus.