Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Kemurnian > 99,0% (HPLC) Kualitas Tinggi Pabrik
Pasokan Sitagliptin Phosphate Monohydrate Related Intermediate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Asam Trifluorofenilasetat CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Jeneng Kimia | 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pirazin Hidroklorida |
sinonim | Sitagliptin Triazole Hydrochloride;Sitagliptin Intermediate A |
Nomer CAS | 762240-92-6 |
Nomer CAT | RF-PI1193 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C6H7F3N4·HCl |
Bobot Molekul | 228.60 |
Titik Lebur | 236.0~246.0 ℃ |
Kelarutan | Larut ing Metanol |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Kristal Putih nganti Putih |
Identifikasi dening HPLC | Wektu retensi sampel cocog karo standar referensi |
Identifikasi dening IR | tundhuk |
Mundhut ing Pangatusan | <0,50% |
Zat sing gegandhengan | |
Sembarang Impurity Single | <0,50% |
Total Impurities | <1.00% |
Logam abot | <20 ppm |
Kemurnian / Metode Analisis | > 99,0% (HPLC) |
Standar Tes | Standar Perusahaan |
Panggunaan | Intermediate saka Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
![1](https://a395.goodao.net/uploads/15.jpg)
![](https://a395.goodao.net/uploads/23.jpg)
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) minangka perantara saka Sitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), yaiku inhibitor DPP4 selektif oral-bioavailable sing ditemokake liwat optimalisasi kelas inhibitor DPP4 sing asale saka β-aminoacid.Iki nyuda kegiatan DPP4 kanthi cara sing terus-terusan sawise administrasi sapisan saben dina, njaga tingkat sirkulasi GIP lan GLP1 sing utuh sawise mangan ing studi akut lan kronis lan nyuda tingkat glukosa getih tanpa paningkatan hipoglikemia sing signifikan.Sitagliptin Phosphate (STG) digunakake kanggo nambani DM tipe 2 amarga nambah kontrol glikemik kanthi nambah tingkat hormon incretin aktif, GLP-1 (peptida-1) lan GIP (glucose-dependent insulinotropic peptide).STG disetujoni dening FDA ing 2006.
-
Sitagliptin CAS 486460-32-6 Kemurnian >99,0% (HPLC...
-
Sitagliptin Phosphate Monohydrate CAS 654671-77...
-
2,4,5-Asam Trifluorofenilasetat CAS 209995-38-...
-
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
-
Sitagliptin Triazole Hydrochloride CAS 762240-9...
-
Sitagliptin Phosphate Monohydrate Intermediate...