tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Kemurnian >98,0% (HPLC) Palbociclib Intermediate Factory
Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butil 4-(6-Nitropyridin-3-yl)piperazin-1-Karboksilat CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pirimidin-7(8H)-siji CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pirimidin-7-siji CAS 1013916-37-4
Jeneng Kimia | tert-Butil 4-(6-Nitropyridin-3-yl)piperazin-1-Karboksilat |
sinonim | 1-Boc-4-(6-Nitro-3-Pyridyl) piperazine;4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butil 4-(6-Nitro-3-Pyridinyl)-1-Piperazinekarboksilat |
Nomer CAS | 571189-16-7 |
Nomer CAT | RF-PI1850 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C14H20N4O4 |
Bobot Molekul | 308.33 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Coklat cahya nganti bubuk coklat |
Kemurnian / Metode Analisis | > 98,0% (HPLC) |
LCMS | Konsisten karo Struktur |
Mundhut ing Pangatusan | <1.00% |
Total Impurities | <2.00% |
Test Standar | Standar Perusahaan |
Panggunaan | Penengah Palbociclib (CAS: 571190-30-2) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
tert-Butyl 4-(6-nitropyridin-3-yl) piperazine-1-carboxylate (CAS: 571189-16-7) minangka perantara saka Palbociclib (CAS: 571190-30-2).Palbociclib (uga dikenal minangka nomer senyawa PD-0332991) minangka obat eksperimental kanggo perawatan kanker payudara sing dikembangake dening Pfizer.Iki minangka inhibitor selektif saka kinase sing gumantung karo cyclin CDK4 lan CDK6.Palbociclib ngalangi progresi siklus sel saka fase G1 menyang S kanthi nyandhet fosforilasi retinoblastoma (RB) gumantung CDK4/6.Palbociclib wis digunakake kanggo perawatan kanker payudara metastatik HER2 negatif, reseptor estrogen (ER).