Vidarabine (Ara-A) CAS 5536-17-4 Purity≥99.0% (HPLC) Kualitas Tinggi Pabrik
Produsen Pasokan Arabinonucleosides Intermediet kanthi Kemurnian Tinggi
Vidarabine;Ara-A;CAS: 5536-17-4
Arabinofuranosyluracil;Ara-U ;CAS: 3083-77-0
Cytarabine;Ara-C;CAS: 147-94-4
Jeneng Kimia | Vidarabine |
sinonim | Ara-A;Arabinoadenosin;Adenine 9-β-D-Arabinofuranoside;Vira-A |
Nomer CAS | 5536-17-4 |
Nomer CAT | RF-PI220 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C10H13N5O4 |
Bobot Molekul | 267.25 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Kristal Putih utawa Off-White |
Kelarutan | Bening Tanpa Warna |
Kemurnian / Metode Analisis | ≥99,0% (HPLC) |
Kandungan UV | ≥98% (ing Basis Kering) |
Rotasi Spesifik [a]D20 | -56,0°~-65,0° (C=1 ing DMF) |
Adenine | ≤0,50% |
Adenosin | ≤0,50% |
Ara-U | ≤0,50% |
Titik Lebur | 260.0~265.0 ℃ |
Logam abot | ≤20ppm |
Standar Tes | Standar Perusahaan |
Suhu panyimpenan | Simpen ing 0 ~ 8 ℃ |
Panggunaan | API;Perantara Farmasi |
Paket: Botol, tas Aluminium foil, Drum karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
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Vidarabine (CAS: 5536-17-4), minangka obat antivirus sing aktif nglawan virus herpes simplex lan varicella zoster.Vidarabine (CAS: 5536-17-4) minangka neurotransmitter sing tumindak minangka agonis endogen sing disenengi ing kabeh subtipe reseptor adenosin.Vidarabine (CAS: 5536-17-4) minangka inhibitor A siklase lan DNA Polimerase.Adenine 9-beta-D-arabinofuranoside (ara-A) minangka nukleosida purin sing diprodhuksi sacara sintetik sing digunakake ing riset sinyal sel.Wis umum digunakake ing riset anti-virus karo hepadnaviridae lan virus herpes simplex.Nukleosida ara-A ngganggu sintesis DNA virus, nanging mung ing wangun fosforilasi aktif.
Vidarabine (CAS: 5536-17-4) minangka antibiotik nukleosida sing diisolasi saka Streptomyces antibioticus.Nduwe sawetara sifat antineoplastik lan nduweni aktivitas spektrum sing amba marang virus DNA ing kultur sel lan aktivitas antivirus sing signifikan marang infeksi sing disebabake dening macem-macem virus kayata virus herpes, VIRUS VACCINIA lan virus varicella zoster.Vidarabine (CAS: 5536-17-4) bisa nyandhet mutan HSV lan VZV sing tahan asiklovir / kurang TK, amarga difosforilasi dadi vidarabine-trifosfat aktif dening kinase seluler lan ora gumantung marang aktivasi ing TK viral
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