L-Arginine Hydrochloride CAS 1119-34-2 (H-Arg-OH·HCl) Assay 99.0~101.0% Factory High Quality

L-Arginine Hydrochloride (H-Arg-OH·HCl) (CAS: 1119-34-2) is used in biochemical research, reduce blood amm onia, treat liver coma drug, can also be used in amino acid drugs, is an important component of amino acid infusion and comprehensive amino acid preparation, can be used as a nutrient supplement. L-Arginine Hydrochloride uses and applications include: Dietary supplement, nutrient in foods, pharmaceuticals intermediates. Amino Acid Drugs. L-Arginine Hydrochloride is used in the treatment of heart and circulatory diseases. It is a precursor of nitric oxide synthesis that induces vasodilation in vivo, there by relaxing blood vessels. It is also used in the treatment of angina and other cardiovascular problems. It is an important intermediate in the urea cycle and involved in the detoxification of nitrogenous wastes. It is commonly used in cell culture media and drug development.

1119-34-2 - Test
Transmittance of Solution
Take lg of this product, Add 10ml of water to dissolve, according to ultraviolet-visible spectrophotometry (General rule 0401 ), measure the transmittance at 430nm wavelength, not less than 98.0%.
Sulfate
Take 0.5g of this product and check it according to law (General rule 0802). Compared with the control solution made of 0.02% of standard potassium sulfate solution, it should not be more concentrated ().
Phosphate
Take 0.4g of this product, place it in the crucible, add 0.3g of magnesium nitrate and 5ml of water, put it in a water bath and evaporate to dryness, burn it with small fire until it is completely ash, add 5ml of water and 3ml of sulfuric acid solution (1- 4), slowly heat for 5 minutes, heat 10ml of water, filter, put the filtrate in a colorimetric tube, and wash the filter residue with an appropriate amount of hot water, add ammonium molybdate solution [take ammonium molybdate 0.5g, add sulfuric acid solution (3-100) 10ml to dissolve] and phosphorus test solution 1ml each, heat at 60°C for 10 minutes, such as blue, with standard phosphate solution (precision weigh 0.143g of potassium dihydrogen phosphate, put in 1000ml measuring flask, add appropriate amount of water to dissolve and dilute to the scale) 0.02% ml of control solution prepared by the same method should not be deeper ().
ammonium salt
Take 0.10g of this product and check it according to law (General rule 0808). Compared with the control solution made of 0.02% of standard ammonium chloride solution, it shall not be deeper ().
Protein
Take lg of this product, Add 10ml of water to dissolve, add 5 drops of 20% trichloroacetic acid solution, and no precipitation is allowed.
Other Amino Acids
Take an appropriate amount of this product, add water to dissolve and dilute to make a solution containing about 10 mg per lml as a test solution; Take 1ml for precision measurement and put it in a 500ml measuring flask, dilute to scale with water, shake, as a control solution; Take the appropriate amount of arginine and lysine hydrochloride in the same flask, water was added to dissolve and diluted to prepare a solution containing about 0.4mg each per 1ml as a system-suitable solution. According to the thin layer chromatography (General 0502) test, Draw 5 u1 of each of the above three solutions, respectively point on the same silica gel G thin layer plate, with N-propanol-concentrated ammonia solution (2:1) as the developing solvent, expand, dry, spray with ninhydrin in acetone solution (1- 50 ), and heat at 105°C until spots appear, and examine immediately. The control solution should show a clear spot, and the system applicable solution should show two completely separated spots. The test solution should not have more than one impurity spot, and the color should not be deeper (0.2%) than the main spot of the control solution.
Loss on Drying
Take this product, dry at 105°C for 3 hours, loss of weight shall not exceed 0.2% (General rule 0831).
Ignition Residue
Not more than 0.1% (General rule 0841).
Iron Salt
Take 2.0g of this product and check it according to law (General rule 0807). Compared with the control solution made of 0.001% of standard iron solution, it should not be deeper ().
Heavy Metals
Take 2.0g of this product, add 23ml of water and 2ml of acetate buffer (pH 3.5) to dissolve, and check according to law (General rule 0821 first law), containing heavy metals shall not exceed 10 parts per million.
Arsenic Salt
Take 2.0g of this product, add 23ml of water to dissolve, add hydrochloric acid 5mU to check according to law (General rule 0822 first law), should comply with the provisions (0.0001%).
Pyrogen
Take this product, add Sterile Water for Injection dissolved and diluted to make a solution containing 50mg per lml, check according to law (General rule 1142), dose according to rabbit body weight per lkg injection 10ml, should comply with the regulations. (For injection)
Chlorine Content
Take about 0.35g of this product, precision weighing, add 20ml of water to dissolve, add 2ml of dilute acetic acid and 8~10 drops of bromophenol blue indicator solution, and use silver nitrate titration solution (0.lmol/ L) titrated to blue-purple. Each 1 ml of silver nitrate titration solution (0.1 mol /L) corresponds to 3.545mg of C1. The chlorine content shall be 16.5%-17.1% based on the dry product.
1119-34-2 - Content Determination
Take this product about 0.1g, precision weighing, add anhydrous formic acid 3ml to dissolve, add glacial acetic acid 50ml and Mercury acetate test solution 6ml, according to the potential titration method (General rule 0701), with perchloric acid titration solution (0.1 mol /L) titration, and the results of the titration were corrected with a blank test. Each 1 ml perchloric acid titration solution (0.1 mol /L) corresponds to 10.53mg of C6H14N402. HCl.