4-Benzyl-2-Hydroxymorpholin-3-one CAS 287930-73-8 Puritas >99.0% (HPLC) Aprepitant Factory medium
Ducens manufacturer ac elit
Intermedia Aprepitantis (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-one CAS 287930-73-8
(R) -1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com
| Nomen chemicum | 4-Benzyl-2-Hydroxymorpholin-3-one |
| Synonyma | 4-Benzyl-2-Hydroxy-Morpholin-3-unum;2-Hydroxy-4-(Phenylmethyl) -3-Morpholinone;Aprepitant Impuritas 48;Fosaprepitant immunditia 23;Aprepitant medium |
| CAS Number | 287930-73-8 |
| CATTUS Number | RF2660 |
| Stock Status | In Stock, Productio Ascendite ad Tons |
| Formulae hypotheticae | C11H13NO3 |
| M. Pondus | 207.23 |
| Liquescens punctum | 134.0 ad 138.0℃ |
| Ferveret | 441.7±45.0℃ |
| Density | 1.292±0.06 g/cm3 |
| Solubilitas in aqua | DMSO (paulo), Methanol (paulo, Calefacta) |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Aspectus | White ad Off-Crystal pulveris |
| Puritas / Analysis Methodus | >99.0% (HPLC) |
| Liquescens punctum | 134.0 ad 138.0℃ |
| Aqua (auctore Karl Fischer) | <0.50% |
| Residere in Ignition | <0.20% |
| Totalis immunditias | <1.00% |
| Proton NMR Spectrum | Conformat ut Structure |
| Test Standard | Enterprise Standard |
| Consuetudinem | Intermedia Aprepitantis (CAS: 170729-80-3) Antiemeticae medicamenti |
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4-Benzyl-2-Hydroxymorpholin-3-unum (CAS: 287930-73-8), medium est Aprepitantis (CAS: 170729-80-3), medicinae antiemetica usus.Aprepitans est neurokinin-1 (NK-1) receptor antagonista et pertinet ad agentes vomitum in chemotherapy cancri tractandis.Primum feliciter a Merck Company (German).Mense Martio MMIII, US Cibus et medicamentum Administration approbavit ut usus in curatione chemotherapy vomitus esset.Hoc productum magnam electionem selectivam cum hominibus habet dum humilem affinitatem habet cum receptore serotonino, dopamine et glucocorticoidei affinitatis.Aprepitant, cum receptore inhibitoribus 5-HT3 (ut hydrochloridi ondansetron) et dexamethasone corticosteroideo conjuncta, cisplatino-acuta et remoto (vel) emesi remoto, ulterius sublevare possunt.Hoc medicamento soli applicando aliquem effectum praecavendum habere potest.
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