7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Puritas >99.0% (HPLC)
Ruifu Chemical Supple intermedia de Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
acetaldehyda Diethyl acetalis CAS 3616-56-6
trans-4-dimethylaminocrotonic Acidum hydrochloridum CAS 848133-35-75
Diethylphosphonoaceticum acidum CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-one CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl) -7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5
Nomen chemicum | 7-Chloro-6-Nitro-4-Hydroxyquinazoline |
Synonyma | 7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-unum;7-Chloro-6-Nitroquinazolin-4(3H)-one |
CAS Number | 53449-14-2 |
CATTUS Number | RF-PI2030 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C8H4ClN3O3 |
M. Pondus | 225.59 |
Sensibilitas | Calor Sensitiva |
Solubilitas | Leviter solutum in Dimethylformamide |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Lumen Yellow ut lux Brown Pulvis |
Lepidium sativum (HPLC) | Retention Time of Sample should Matches with Standard |
Puritas / Analysis Methodus | >99.0% (HPLC) |
Liquescens punctum | 300.0~303.0℃ |
Aqua Content (KF) | <0.50% |
Residere in Ignition | <0.30% |
immunditia 1 | <0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2) |
immunditia 2 | <0.50% (5,7-Dichloro-4[1H]quinazolinone) |
immunditia 3 | <1.00% (7-Chloro-8-Nitro-4[1H]quinazolinone) |
Alia immunitas | <0.20% |
Totalis immunditias | <1.00% |
Metalla gravia (ut Pb) | <20ppm |
Infrared Imaginis | Conformat ut Structure |
Proton NMR Spectrum | Proton NMR Spectrum |
Test Standard | Enterprise Standard |
Consuetudinem | Medium Afatinib, Afatinib Dimaleate |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore
7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) intermedius est Afatinib Dimaleate (CAS: 850140-73-7).Afatinib irreversibilis est familia interclusorum ErbB qui informationes transmissionis supprimunt et vias maiores impeditas quae in incremento et divisione cellae cancri implicantur.Quia ErbB familiae informationes transductionis mechanismi possunt per plures homodimersos et heterodimeros Urguere, simultanea inhibitio plurium membrorum familiarium ErbB (ut EGFR, HER2, ErbB3 et ErbB4) efficaciter interrumpens informationes transductionem amni possunt.Afatinib tractare certum genus cancri pulmonis (cancri pulmonis non parvae) quae in alias partes corporis diffusa est.Genus medicamentorum quod inhibitores kinasi notum est.Is incrementa cancer cellulis retardando vel impediendo operatur.interdum in quibusdam tumoribus quibusdam (epiderma receptor-EGFR) alligat.