7-Fluoro-6-Nitroquinazolin-4(1H)-one CAS 162012-69-3 Puritas >99.0% (HPLC)

Description:

Nomen chemicum: 7-Fluoro-6-Nitroquinazolin-4(1H)-one

CAS: 162012-69-3

Puritas: >99.0% (HPLC)

Yellow vel rufo flavo Crystal aut pulveris

Afatinib Dimaleate (CAS: 850140-73-7)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Descriptio:

Ruifu Chemical Supple intermedia de Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
acetaldehyda Diethyl acetalis CAS 3616-56-6
trans-4-dimethylaminocrotonic Acidum hydrochloridum CAS 848133-35-75
Diethylphosphonoaceticum acidum CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-one CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl) -7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Chemical Properties:

Nomen chemicum	7-Fluoro-6-Nitroquinazolin-4(1H)-one
Synonyma	7-Fluoro-6-Nitroquinazolin-4(3H)-one;7-Fluoro-4-Hydroxy-6-Nitroquinazoline;7-Fluoro-6-Nitroquinazolin-4-ol;7-Fluoro-6-Nitro-4-Hydroxyquinazoline;7-Fluoro-6-Nitro-1H-Quinazolin-4-one
CAS Number	162012-69-3
CATTUS Number	RF-PI2025
Stock Status	In Stock, Productio Ascendite ad Tons
Formulae hypotheticae	C8H4FN3O3
M. Pondus	209.13
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Aspectus	Yellow vel rufo flavo Crystal aut pulveris
1 H NMR Spectrum	Congruunt cum Structure
Puritas / Analysis Methodus	>99.0% (HPLC)
Damnum in Siccatio	<0.50%
Totalis immunditias	<1.00%
Proton NMR Spectrum	Conformat ut Structure
Test Standard	Enterprise Standard
Consuetudinem	Afatinib Dimaleate (CAS: 850140-73-7)

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

FAQ:

Applicatio:

7-Fluoro-6-Nitroquinazolin-4(1H)-unum (CAS: 162012-69-3) medium est Afatinib Dimaleate (CAS: 850140-73-7).Afatinib irreversibilis est familia interclusorum ErbB qui informationes transmissionis supprimunt et vias maiores impeditas quae in incremento et divisione cellae cancri implicantur.Quia ErbB familiae informationes transductionis mechanismi possunt per plures homodimersos et heterodimeros Urguere, simultanea inhibitio plurium membrorum familiarium ErbB (ut EGFR, HER2, ErbB3 et ErbB4) efficaciter interrumpens informationes transductionem amni possunt.Afatinib est medicamentum approbatum ad tractationem carcinomatis pulmonis non parvae cellulae (NSCLC), a Boehringer Ingelheim evoluta.Agit angiokinase inhibitor.Sicut lapatinib et neratinib, afatinib est tyrosinus kinasus inhibitor (TKI) qui etiam irrevocabiliter vetat factorem 2 (Her2) et factor incrementi epidermalis receptor 2 (Her2) et kinases receptae incrementi epidermalis.Afatinib non solum activa contra mutationes EGFR iaculis a generatione prima TKIs likeerlotinib vel gefitinib, sed etiam contra illas therapias normas non sensitivas.Propter additam actionem contra Her2, investigatur pro carcinomate pectoris necnon aliis EGFR et Her2 carcinomata agitata.