Betamethasone CAS 378-44-9 Puritas 97.0%~ 103.0% API Factory High Purity Lorem Image

Betamethasone CAS 378-44-9 Puritas 97.0%~ 103.0% API Factory Puritas

Description:

Chemical Name: Betamethasone

CAS: 378-44-9

Aspectus: Albus vel Fere Albus Crystallinus Pulvis

Puritas: 97.0%~ 103.0% of C22H29FO5, basis aridae

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Product Detail

Product Tags

378-44-9 - Descriptio:

Commercial Supple Betamethasone cum High puritate et Stabilis Quality
Chemical Name: Betamethasone
CAS: 378-44-9

378-44-9 -Chemical Properties:

Nomen chemicum	Betamethasone
Synonyma	Betamethasone Base;9alpha-Fluoro-16beta-Methylprednisolone;9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione;(11beta,16alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
CAS Number	378-44-9
Stock Status	In Stock, Productio Ascendite ad Tons
Formulae hypotheticae	C22H29FO5
M. Pondus	392.47
Liquescens punctum	235.0~ 237.0℃
Shipping Condition	Sub Ambient Temperature
COA & MSDS	Praesto
Brand	Ruifu Chemical

378-44-9 -Specifications:

Item	Specifications
Aspectus	Alba aut fere alba Crystallina pulveris
Lepidium sativum	Infrared effusio
Lepidium sativum B *	Tenuis Chromatographic sativum Test
Imprimis Rotatione Optica	+18.0° ad +126.0° (Ratio ex Sicca Basis)
Individual Impurity	≤1.00%
Totalis immunditias	≤2.00%
Residua Solvent Methanolum	≤3000ppm
RELICTUM Solvents Chloroforme	≤60ppm
Damnum in Siccatio	≤0.50% (sicco ad CV", III horas)
Residere in Ignition	≤0.20%
Puritas / Analysis Methodus	97.0%~ 103.0% of C22H29FO5 Calculatae in Basis aridae
Test Standard	Pharmacopoeia Sinica (CP);EP10.0 et USP 42
Packaging et repono	Strictis vasis conserva.Copia inter 2℃ et 30℃.
Applicationem	Active Pharmaceutical Ingredient (API)

Sarcina & Repono:

Sarcina:Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris.
Repono Condition:Continentem arcte clausam et in loco frigido, sicco (2~30℃) reponunt et a cellis bene ventilatis ab substantiis incompossibilibus.Absiste a firmo lumine et calore, humore.
Naviportans:Libera ad mundum ab aere, per FedEx / DHL Express.Ieiunium et certas traditiones provide.

commoda:

FAQ:

378-44-9 — Periculum et Salus;

Risk Codes R40 - Limited evidentia carcinogenici effectus
R48/20/21 -
R61 - Sit partus nocumentum
Safety Description S22 - Pulverem ne respirare.
S36 - gere idoneos tutelae vestis.
S45 - In casu casu vel si bene sentis, consilium medicinae statim quaere (titalam quoties fieri potest).
S53 - expositionis vitandae - speciales instructiones ante usum obtinendum.
WGK Germania 2
RTECS TU4000000
HS Codicis 2937229000
Toxicity LD50 oralis in muris: > 4500mg/kg

378-44-9 -Applicatio:

Betamethasone (CAS: 378-44-9), pertinet ad corticosteroides adrenales, est isomer dexamethasonis, et munus betamethasonis simile est prednisolone et dexamethasone, habet anti-inflammatorium, anti-rheumaticum, anti-allergicum et suppressionem. immunis et aliis effectibus pharmacologicis, eius effectus anti-inflammatorii validior est quam dexamethasone, triamcinolone, hydrocortisone etc., potest minuere et impedire responsionem textus ad inflammationem et calorem, ruborem et tumorem ex inflammatione locali non-infectiosi causata, inde minuendo. effectus inflammationis, effectus anti-inflammatorii huius producti 0.3mg, aequale est dexamethasone 0.75mg, valium 5mg vel 25mg cortisone.Betamethasone sodium retentionis effectus est centies plus quam hydrocortison, in prima hypofunctione adrenalis, una cum glucocorticoide ad theraphim repositum adhiberi potest, et adhibetur ad impediendam vel inhibendam responsionem cellulam mediatam immunem, allergicas motus retardans et immunem primariam reducendo. responsio expansio, adhibetur pro syndrome aldosterone et renin minore et neuropathia autonomica hypotensi orthostatica inducenda.In statu betamethasone etiam adhibetur ad curationem rheumatoidis arthritis activae, arthritis rheumatoidis, lupus, gravi asthma bronchialis, dermatitis vehemens, leukemia acuta, dermatitis atopica, eczema, neurodermatitis, dermatitis seborrheica, et pruritus et curatio quorundam contagionum comprehensiva.Productum contraindicatum est in historia gravi psychiatrica, ulcere duodenali activo, anastomosi gastrointestinali recenti, gravius osteoporosis, aperta diabete, gravi hypertensione, virus, bacterial, fungalorum contagione, quae usu agentium antimicrobialium, thrombophlebitis, contagios cutis ut impetigo, tinea, pruritus, et sic porro.

378-44-9 - USP35 Standard:

Betamethasone
C22 H29FO5 392.46
Pregna-1,4-diene-3,20-dione,9-fluoro-11,17,21-trihydroxia-16-methyl-, (11,16)-.
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione [378-44-9].
Betamethasone non minus quam 97.0 centesimas continet et non plus quam 103.0 centesimas C22H29FO5, fundamento siccato computatum.
Packaging ac repono-Conserve in strictis vasis.Copia inter 2℃ et 30℃.
USP Reference signa <11>-
USP Betamethasone RS
Identification-
A: Absorptio infrared <197M>.
B: Tenuis chromatographicae sativum Test <201>-
Solutio test-Para solutionem Betamethasonis in alcohole dehydrato continens 0.5 mg per mL.
Solvendo explicandi ratio: mixtura chloroformi et diethylamini (2:1).
Procedure-Perge ut in capitulo ordinatur, nisi maculas collocare cum acido sulphurico diluto diluto leviter spargendo (I in 2) et in patina calida vel sub lucerna calefaciendo, donec maculae appareant.
Imprimis rotationis <781S>: inter +118 et +126, in fundamento siccato computata.
Solutio test: 5 mg per mL, in methanolum.
Damnum in siccitate 731-Arida ad 105 pro 3 horis: non plus quam 1.0% sui ponderis amittit.
Residuum ignitionis 281: non plus quam 0.2%, platinum uasculum adhibitum.
immunditiae ordinariae 466-.
Solutio test: methanolum.
Solutio Vulgate: methanolum.
Applicatio voluminis: 10 µL.
Eluant: mixtura toluene, acetone, yl ethyl ketonis, et acidi formic (55:20:20:5), in conclavi nonquilibrato.
Visualization: 5.
Assay-
Mobile phase-Para saccata et sparsa mixtura aquae et acetonitrilis (63:37).Fac si opus sit adaptationes (cf. Systema Suitability sub Chromatographia 621).
Solutio vexillum internum - Para solutionem propylparaben in alcohole notam retractionem circiter 0,25 mg per mL habentem.
Praeparatio Standard-Dissolve quantitatem USP Betamethasone RS accurate perpensam in alcohole ad solutionem obtinendam habens notam intentionem circiter 0,2 mg per mL.Translatio 10.0 mL solutionis huius ad phialam idoneam, et solutionem normae internae 10.0 mL adde, ad obtinendam Standardi praeparationem, cum notis concentrationis circiter 0.1 mg betamethasonis et circa 0.125 mg propylparabenis per mL.
Praeparatio-usura de 80 mg Betamethasonis, accurate perpensis, para ut ordinatur ad praeparationem Latinam.
Systema chromatographicum (cf. chromatographia 621) - chromatographum liquidum cum detectore 240-um instructum et 4.6-mm × 25-cm columnam quae fasciculum L1.Rate fluxus circiter 1.0 mL per minute est.chromatographum Praeparatio Vulgata, et apicem responsionum ad procedendum directae: retentio relativa tempora sunt circiter 1.0 pro betamethasone et 1.4 pro propylparaben;resolutio, R inter betamethasone et propylparaben non minus quam 3.0;et vexillum relativum declinationis ad injectiones replicatas non plus quam 2.0%.
De modo procedendi-Separatim injiciunt paria volumina (circa 10 µL) praeparationis vexilliferae et praeparatio in chromatographa, chromatogrammata notare et responsa ad cacumina maiora metire.Quantitatem in mg, C22H29FO5 computa in portione Betamethasone sumpta formula;
800C(RU/RS)
in quo C est intentio, in mg per mL, USP Betamethasone RS in praeparatione Vulgata;and RU and RS are the top height of the betamethasone proportions of the top and the standard of the vertex interni consecuti from the Asssay praeparation and the Latin preparation, respectively.