Bicalutamide CAS 90357-06-5 API Factory Provectus Prostatae Cancer
Manufacturer Supple cum High puritate et stabulo Quality
Nomen: Bicalutamide
CAS: 90357-06-5
Bicalutamide in curatione Cancri Prostatae Provectae
API High Quality, Commercial Production
Nomen | Bicalutamide |
Synonyma | N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide |
CAS Number | 90357-06-5 |
CATTUS Number | RF-API76 |
Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
Formulae hypotheticae | C18H14F4N2O4S |
M. Pondus | 430.37 |
Repono Temperature | 2-8℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White Crystalline pulveris |
Lepidium sativum | IR: Imaginis specimen correspondet relationis vexillum |
Lepidium sativum B * | HPLC: Retentionis tempus solutionis maioris cacuminis sample solutionis respondet solutionis vexillum |
Lepidium sativum C* | Organicum Fluoride Lepidium sativum |
Solubilitas | Gratis solutum in Acetone et Tetrahydrofuran, Paulo solutum in Ethyl Acetate. |
Liquescens punctum | 191.0~ 195.0℃ |
Aqua Content (per KF) | ≤0.20% |
Fluoride Content | 15.9%~ 18.5% |
Damnum in Siccatio | ≤0.50% |
Residere in Ignition | ≤0.10% |
Metalla gravis | ≤10ppm |
RELICTUM Solvents | |
Tetrahydrofuran | ≤0.072% |
Toluene | ≤0.089% |
N-Hexane | ≤0.029% |
Acetone | ≤0.50% |
Ethyl Acetate | ≤0.50% |
Substantiae cognatae | |
N,N'-Dimethyl Acetamide | ≤0.109% |
Bicalutamide Aminobenzonitrile | ≤0.10% |
Bicalutamide Related Compone A Isomer A | ≤0.10% |
Bicalutamide Related Compone A Isomer B | ≤0.10% |
Desfluoro Bicalutamide | ≤0.20% |
2-Fluoro Bicalutamide | ≤0.20% |
Deoxy Bicalutamide | ≤0.20% |
Bicalutamide Sulfide | ≤0.10% |
Quis non specificatus immunditia | ≤0.10% |
Totalis immunditias | ≤0.50% |
Magnitudo particula | 90%<10um;L%<5um |
Assay | 98.0% ~ 102.0% (ex exaruit basis) |
Microbiological Test | |
Summa Viable Aerobic Comitis | ≤500CFU/g* |
Fermenta et Molds | ≤50CFU/g* |
Fasciae vita | XXIV Menses |
Test Standard | Enterprise Latin;USP Standard |
Consuetudinem | API, in curatione Cancri Prostatae Provectae |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
Bicalutamide (CAS: 90357-06-5) est antagonista non steroidalis androgeni, quae cum androgenio receptori cum androgen certat, impedimentum cellularum androgenium impedit, et ligamen androgenis ad organum scopo vetat.Cum androgen receptori obligat formas receptantis complexi, quae nucleum intrat et cum nucleoprotein componitur, consequenter incrementum cellae tumoris inhibens.Potest esse sicut medicamentum primae lineae pro palliativa curatione cancri prostatae provectae.Bicalutamide in Britanniae Regnum, primum eius mercatum universale, deductum est ad tractationem cancri prostatae in compositione cum castratione LHRH analogi vel chirurgici.Non-steroidale, peripheraliter antiandrogenium selectivum, bicalutamide vetat actionem dihydrotestosteronis et testosteronis in locis scopo, vinculo competitive ad cytosolic androgeni receptoris.Bene toleratum est parem non esse significantes cardiovasculares et metabolicos effectus propter commodum cuiuslibet actionis steroidei carere.Efficacia bicalutamidis sicut monotherapia amet demonstrata est.Rates responsionis pollicentes nuntiaverunt etiam in tractando carcinomata colorectales, pectus, pancreas et non parvas cellula pulmonis.