Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acidum CAS 486460-00-8 Puritas ≥99.5%
Supple Sitagliptin Phosphate Monohydratorum intermedia:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydratum API CAS 654671-77-9
Acidum trifluorophenylaceticum 2,4,5-
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acidum CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydratum Intermediate CAS 486460-21-3
Nomen chemicum | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl) |
Synonyma | (R) -Sitagliptin N-Boc-Acid Impurity |
CAS Number | 486460-00-8 |
CATTUS Number | RF-PI1192 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C15H18F3NO4 |
M. Pondus | 333.31 |
Liquescens punctum | 136.0~ 138.0℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White pulveris |
Lepidium sativum ab HPLC | Retentionis tempus Sample concordat cum Reference Standard |
Damnum in Siccatio | ≤0.50% |
Cinis sulphated | ≤0.50% |
Metalla gravis | <20ppm |
Isomer | ≤0.50% |
Substantiae cognatae | |
immunditiam A | ≤0.50% |
Alia alia immunditia | ≤0.50% |
Totalis immunditias | ≤0.50% |
Puritas | ≥99.5% (HPLC) |
Test Standard | Enterprise Standard |
Consuetudinem | Sitagliptin Phosphate Monohydratorum medium (CAS: 654671-77-9) |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;A luce et humore protege.
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acidum (CAS: 486460-00-8) medium magni momenti est ad parandum sitagliptinum.Sitagliptinphosphate est prima dipeptidase -IV(DPP-4) inhibitor a FDA in 2006 approbata. Ponitur pro curatione speciei II diabete melliti.Patet effectum hypoglycemicum cum solum vel coniuncte cum metformin et pioglitazone adhibitum, et tutum est cum paucis reactionibus adversantibus bene tolerari.Mense Augusto 2009 pharmacum ab Unione Europaea probatum est tamquam medicamentum primae lineae pro curatione speciei 2 diabete.Post 2011, aliae post aliae nationes phosphate sitagliptin et alpha glycosidasi inhibitores seu insulinum compositum probaverunt.Sitagliptin phosphas primus est FDA-approbatus dipeptidyl peptidase-IV inhibitor adhibendus in tractatione speciei 2 diabete longe, sub commercii nomine Januvia.