Candesartan Cilexetil CAS 145040-37-5 Puritas >99.0% (HPLC) API Factory

Description:

Chemical Name: Candesartan Cilexetil

CAS: 145040-37-5

Puritas: >99.0% (HPLC)

Aspectus: Alba ad Off-White Crystalline pulveris

Angiotensin II Receptor Antagon

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Descriptio:

Ruifu Chemical Supple Candesartan Cilexetil medium cum puritate
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonatis CAS 99464-83-2
Candesartan Cilexetil Intermedia Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0

Chemical Properties:

Nomen chemicum	Candesartan Cilexetil
Synonyma	TCV-116;1-(((Cyclohexyloxy)carbonyl)oxyl)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H -benzo[d]imidazole-7-Carboxylate
CAS Number	145040-37-5
CATTUS Number	RF-PI1891
Stock Status	In Stock, Productio Ascendite ad Tons
Formulae hypotheticae	C33H34N6O6
M. Pondus	610.66
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Aspectus	Alba ad Off-White Crystalline pulveris
Lepidium sativum HPLC	Retentionis tempus cacuminis maioris in chromatogrammis sample respondet illi quod in chromatogrammo cum norma consecuta est.
Lepidium sativum IR	IR effusio spectri infrarubri idem est ac Candesartan Cilexetil vexillum referens
Solutio in claritate et colore	Solutio in chloroformi ad 5% patet et sine colore
Puritas / Analysis Methodus	>99.0% (HPLC)
Liquescens punctum	155.0~160.0℃
Damnum in Siccatio	<0.30%
Residere in Ignition	<0.10%
Metalla gravis	<10ppm
Arsenicum (As)	<1ppm
Particula Size Distributio	90% <30 μm
Impurities organica	per HPLC *
Ethyl Candesartan	<0.15%
Desethyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
Ignota immunditia	<0.15%
Totalis immunditias	<0.60%
Potentiometria	99.0~ 101.0% C33H34N6O6, calculata substantia anhydroae
Organicum volatile immunditia
Methano	<0.30%
Ethanol	<0.50%
Diethyl Ether	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Microbiological Contarnination
Summa Aerobic Microbial comitis	<1000cfu/g
Fingit & Yeasts	<100cfu/g
E.Coli	Absens
Salmonella	Absens
Test Standard	Enterprise Standard
Consuetudinem	API;Antihypertensive agentis

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

FAQ:

Applicatio:

Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) est receptor angiotensin II cum IC50 0,26 nM, usus est in curatione hypertensionis.Candesartan est angiotensin receptator obstructor (ARB) quae sola vel cum aliis agentibus hypertensionem tractari potest.Voce administratur sicut prodrug, candesartan cilexetil, quae celeriter ad metabolitam suam, candesartan, in effusio gastrointestinali, celeriter convertitur.Candesartan sanguinem pressuram demittit per systematis renin-angiotensin-aldosteronis infestas (RAAS);cum angiotensin II certat ad angiotensin II receptorem subtypum 1-typum ligandum, et prohibet sanguinem pressuram augentem effectus angiotensin II.Dissimile angiotensin-convertentis enzyme (ACE) inhibitores, ARBs tussim aridae effectum adversam non habent.Candesartan adhiberi potest hypertensionem tractare, hypertensionem systolicam solitam, hypertrophiam ventriculi sinistri et nephropathiam diabeticam.Potest etiam adhiberi ut jocus agentis ad defectum cordis curationem, dysfunctionem systolicam, infarctum myocardialem et arteriam coronariam.