Ibrutinib Intermedia CAS 330792-70-6 Munditia >98.0% (HPLC)

Description:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Puritas: >98.0% (HPLC)

Aspectus: Off-White ad lux Yellow pulveris

Medium Ibrutinib (CAS: 936563-96-1) 

Contactus: Dr

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E-Mail: alvin@ruifuchem.com


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Intermedia Ibrutinib:

Chemical Properties:

Nomen chemicum 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Synonyma Ibrutinib N-MEDIUM;3-Amino-5-(4-Phenoxyphenyl)pyrazole-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pyrazole;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
CAS Number 330792-70-6
Stock Status In Stock, Productio Ascendite ad Tons
Formulae hypotheticae C16H12N4O
M. Pondus 276.29
Density 1.37±0.10 g/cm3
COA & MSDS Praesto
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Item Specifications
Aspectus Off-White ad lux Yellow pulveris
Puritas / Analysis Methodus >98.0% (HPLC)
Damnum in Siccatio <1.00%
Residere in Ignition <0.50%
Totalis immunditias <2.00%
Metalla gravia (ut Pb) <20ppm
1 H NMR Spectrum Congruunt Structure
Test Standard Enterprise Standard
Consuetudinem Medium Ibrutinib (CAS: 936563-96-1)

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris.

Repono Condition:Repone in vasis signatis in loco frigido et sicco;A luce et humore protege.

commoda:

1

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330792-70-6 - Applicatio:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) medium est Ibrutinib (CAS: 936563-96-1).Ibrutinib ostendit potentem et immedicabilem effectum inhibitorium et selectivity Btk in actione enzymatica.In BCR via actuata DOHH2 cellulae lineae, Ibrutinib vetat autophosphorylationem Btk, phosphorylationem physiologicae subiectae PLCγ Btk, et phosphorylatio ulterioris amni kinasi, ERK cum IC50 11 nM, 29 nM et 13 nM, respectively.Ibrutinib exhibet inductionem cytotoxicitatis notabilem dosi dependens et temporis dependens in cellulis lymphocyticis longis (CLL).Praeterea Ibrutinib inducit cellam mortem secundum viam activationis caspasi et facultatem CLL cellularum impeditas ad prolifeandum post TLR significationis.

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