CAS 361442-04-8 Puritas >99.0% (HPLC) API

Description:

Synonyms: BMS-477118;Onglyza

CAS: 361442-04-8

Puritas: >99.0% (HPLC)

Aspectus: pulveris albi

API, High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Descriptio:

Ruifu Chemical Supple Related Intermedia
CAS 361442-04-8
CAS 945667-22-1
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(R)-(-)-3-Aminopiperidine dihydrochloride CAS 334618-23-4
Boc-3-Hydroxy-1-Adamantyl-D-Glycine CAS 361442-00-4
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
2-(3-Hydroxy-1-Adamantyl)-2-Acidum Oxoaceticum, CAS 709031-28-7

Chemical Properties:

Synonyma	BMS-477118;Onglyza;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-Hydroxy-1-Adamantyl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-Carbonitrile;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-Hydroxytricyclo [3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane. -3-Carbonitrile
CAS Number	361442-04-8
CATTUS Number	RF-PI1991
Stock Status	In Stock, Productio Ascendite ad Tons
Formulae hypotheticae	C18H25N3O2
M. Pondus	315.41
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Aspectus	Alba pulveris
Odor	Proprium
idem	A: IR B: HPLC retentionis Tempus
Puritas / Analysis Methodus	>99.0% (HPLC)
Solutio claritatis aquae	Perspicuus, hyalina, Nulla res Intermissa
Sieve Analysis	Transi Mesh% LXXX
Liquescens punctum	202.0~212.0℃
Damnum in Siccatio	<0.50%
Cinere sulphated	<0.20%
Imprimis Rotationes	+74.0°~+186.0°
una immunditia	<0.50%
Totalis immunditias	<1.00%
Metalla gravis	<10ppm
Arsenicum (As)	<2.0ppm
Duc (Pb)	<1.0ppm
Cadmium (Cd)	<1.0ppm
RELICTUM Solvents	<100ppm
Residua Pesticide	Negative
Microbiologia
Totalis comitis Plate	<1000cfu/g
Fermentum & Mold	<100cfu/g
E. Coli	Negative
S. Aurei	Negative
Salmonella	Negative
Fasciae vita	XXIV Menses ex Manufacture Date si Repono Proprie
Test Standard	Enterprise Standard
Consuetudinem	API;Typus 2 Diabetes Mellitus

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

FAQ:

Applicatio:

( CAS: 361442-04-8) potens, selectiva, convertibilis, auctor et viva dipeptidylus peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor.BMS-477118 habet peotentiales pro specie 2 diabete melliti inquisitionis.BMS-477118Genus 2 diabete medicamentum est quod pancreas movet ad plus insulinum post cibum.Perventum est ab cooperatione AstraZeneca et Bristol-Myers Squibb Societatis et ad inhibitorem DPP-IV pertinet.BMS-477118agit per inhibitionem GLP-l recidat.GLP-I Est hormona quae naturaliter intestino cibo sumta nascitur.Potest secretionem insulinae moderari et utendo glucosi in texturis periphericis roborare.Unius medicamento glucosi sanguinis emendare potest imperium et medicamentum coniunctum BMS-477118 cum Metformin, Sulfonylurea et Thiazolidinedionibus effectum curativum augere possunt.Perducit ad gravem periculum hypoglycemiae eiusque motus adversae similes placebo, tolerantiam meliorem ostendens.Die 31 mensis Iulii anno 2009, BMS-477118 tabulae (Onglyza), novum medicamentum speciei 2 diabete, coniunctim exquisiverunt et elaboraverunt AstraZeneca et Bristol-Myers Squibb ab US FDA approbata est.Semel in die sumi potest ut species 2 diabete tractandi coniuncta cum victu et exercitatione moderandi.