CAS 945667-22-1 Puritas >99.0% (HPLC) API

Description:

CAS: 945667-22-1

Puritas: >99.0% (HPLC)

Aspectus: pulveris albi

API, High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Descriptio:

Ruifu Chemical Supple Related Intermedia
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CAS 945667-22-1
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(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
2-(3-Hydroxy-1-Adamantyl)-2-Acidum Oxoaceticum, CAS 709031-28-7

Chemical Properties:

Synonyma	BMS-477118 Hydrate;Onglyza Hydrate;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-Hydroxy-1-Adamantyl)acetyl]-2-Azabicyclo [3.1.0]hexane-3-Carbonitrile Hydrate;(1S,3S,5S)-2-[(S)-2-Amino-2-[(1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl]acetyl]-2-Azabicyclo [3.1.0 ]Hexane-3-Carbonitrile Hydrate
CAS Number	945667-22-1
CATTUS Number	RF-PI1992
Stock Status	In Stock, Productio Ascendite ad Tons
Formulae hypotheticae	C18H25N3O2·H2O
M. Pondus	333.43
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Aspectus	Alba pulveris
idem	A: IR B: HPLC retentionis Tempus
Puritas / Analysis Methodus	>99.0% (HPLC, On Dried Basis)
Aqua Content (KF)	5.3%~7.3%
Residere in Ignition	<0.20%
una immunditia	<0.50%
Totalis immunditias	<1.00%
Metalla gravis	<10ppm
Arsenicum (As)	<2ppm
Microbiologia
Totalis comitis Plate	<1000cfu/g
Fermentum & Mold	<100cfu/g
E. Coli	Negative
S. Aurei	Negative
Salmonella	Negative
Fasciae vita	XXIV Menses
Test Standard	Enterprise Standard
Consuetudinem	API;Curatio Typus II diabete

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

FAQ:

Applicatio:

API (CAS: 945667-22-1) dipeptidylum peptidase-4 (DPP4) inhibitor selectivum et convertitur qui adhiberi potest ad curationem explicandam pro specie 2 diabetarum.Inhibitor selectivi et convertibilis cum IC50 26 nM et Ki ipsius 1.3 nM.IC50 valor: 26 nM.Scopum: DPP4 in vitro: Inhibitionem constantem habet Ki of 1.3 nM pro DPP4 inhibitionis, quod est 10 duplex potentius quam Sitagliptin (alia duo DPP4 inhibitores) cum Ki inter 13 et 18 nM.Praeterea maiorem proprietatem pro DPP4 demonstrat quam propter enzymes vel DPP8 vel DPP9 (400- et 75- ovile respective).Activa metablitus ejus est duplex imbecillior quam parens.Ambo (CAS: 945667-22-1) eiusque metabolitae valde selectivae sunt (>4000 duplicis) ad praecavendam DPP4 praecavendam cum aliis proteasibus.(CAS: 945667-22-1) degradationem redigit hormonum glucagonum incretini peptidis-similis 1 , effectus augendi et cum meliore β-cellula functionis et suppressionis glucagonis secretion.in vivo coniungitur: Valde efficax est. at eliciens amplificationem dosis-dependens notatam in alvi glucosi in dosi range 0.13-1.3 mg/kg in ob/ob mures ad imperium relatum.