Entecavir Monohydrate CAS 209216-23-9 API

Description:

Chemical Name: Entecavir Monohydrate

CAS: 209216-23-9

Aspectus: Albus vel Fere Albus Crystallinus Pulvis

Medicamentum antivirale in curatione Hepatitis B infectio

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Descriptio:

Manufacturer Supple cum High puritate et stabulo Quality
Chemical Name: Entecavir Monohydrate
CAS: 209216-23-9
Usus est in curatione Hepatitis B Infectio
API High Quality, Commercial Production

Chemical Properties:

Nomen chemicum Entecavir Monohydratorum
Synonyma Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydratorum
CAS Number 209216-23-9
CATTUS Number RF-API79
Stock Status In Stock, Productio Ascendite usque ad Centum chiliogrammata
Formulae hypotheticae C12H17N5O4
M. Pondus 295.3
Liquescens punctum >220℃
Density 1.81
Shipping Condition Uit sub Ambient Temperature
Brand Ruifu Chemical

Specifications:

Item Specifications
Aspectus Alba aut fere alba Crystallina pulveris
Solubilitas Gratis solutum in Dimethylformamide, Paulo solutum in aqua, Ethanol et Methanol.
Lepidium sativum IR Spectrum specimen correspondet relationis vexillum
Lepidium sativum HPLC Retentio tempus specimen probati correspondet relationis vexillum
Aqua Content (per KF) 5.5%~6.5%
Imprimis Rotatione Optica +24.0° ad +30.0° (DMF: MeOH=1:1 C=1%).
Residere in Ignition ≤0.10%
Substantiae cognatae  
Furoentecavir ≤0.10%
Entecavir 1-Epimer ≤0.10%
Entecavir 3-Epimer ≤0.10%
8-Methyoxy Entecavir ≤0.10%
Entecavir 4-Epimer ≤0.10%
8-Hydroxy Entecavir ≤0.10%
4-Dimethylsilyl Entecavir ≤0.10%
Entecavir Related Compone A ≤0.10%
Quis non specificatus immunditia ≤0.10%
Totalis immunditias ≤0.30%
RELICTUM Solvents
Methanol ≤600ppm
Dichloromethane ≤300ppm
Ethyl Acetate ≤1000ppm
Tetrahydrofuran ≤720ppm
Toluene ≤890ppm
Benzyl Chloride ≤1000ppm
Benzyl Sin ≤1000ppm
Microbial Limit
Summa Aerobic Comites ≤100cfu/g*
Fermenta et Molds ≤10cfu/g*
Mus Si non Results
Metalla gravis ≤10ppm
Assay 98.0% ~ 102.0% (HPLC; in anhydrous basis)
Magnitudo particula XCV% particularum sit intra 125um
Test Standard Enterprise Latin;Pharmacopoeia Civitatum Foederatarum (USP) Standard
Consuetudinem Medicamentum antivirale in curatione Hepatitis B infectio

Sarcina & Repono:

sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.

commoda:

1

FAQ:

Applicatio:

Entecavir Monohydratorum (CAS 209216-23-9) est medicamentum antivirale orale adhibitum in curatione infectio virium Hepatitis B (HBV) .Entecavir Monohydratus est nucleosidum analogum (proprie, analogum guaninum) quae transcriptionem transpositionem vetat, DNA replicationem et transcriptionem in vira.Novum genus est acyl guanosini anti-Hepatitis B virus medicinae cum effectibus pharmacologicis sicut Entecavir.Applicatur amet ad curationem Hepatitis adulti Chronici B in qua est replicatio viralis activa, aucta serum transaminase ALT vel laesiones activas ex histologia hepatis ostendit.Entecavir Monohydratorum potens et selectivus inhibitor HBV est, cum EC50 3.75 nM in cellam HepG2.Entecavir res adversae transcriptase inhibitor est.Hepatitis B Virus (HBV) impedit ne quantitatem virium in corpore multiplicando et minuat.

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