Entecavir Monohydrate CAS 209216-23-9 API
Manufacturer Supple cum High puritate et stabulo Quality
Chemical Name: Entecavir Monohydrate
CAS: 209216-23-9
Usus est in curatione Hepatitis B Infectio
API High Quality, Commercial Production
Nomen chemicum | Entecavir Monohydratorum |
Synonyma | Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydratorum |
CAS Number | 209216-23-9 |
CATTUS Number | RF-API79 |
Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
Formulae hypotheticae | C12H17N5O4 |
M. Pondus | 295.3 |
Liquescens punctum | >220℃ |
Density | 1.81 |
Shipping Condition | Uit sub Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba aut fere alba Crystallina pulveris |
Solubilitas | Gratis solutum in Dimethylformamide, Paulo solutum in aqua, Ethanol et Methanol. |
Lepidium sativum IR | Spectrum specimen correspondet relationis vexillum |
Lepidium sativum HPLC | Retentio tempus specimen probati correspondet relationis vexillum |
Aqua Content (per KF) | 5.5%~6.5% |
Imprimis Rotatione Optica | +24.0° ad +30.0° (DMF: MeOH=1:1 C=1%). |
Residere in Ignition | ≤0.10% |
Substantiae cognatae | |
Furoentecavir | ≤0.10% |
Entecavir 1-Epimer | ≤0.10% |
Entecavir 3-Epimer | ≤0.10% |
8-Methyoxy Entecavir | ≤0.10% |
Entecavir 4-Epimer | ≤0.10% |
8-Hydroxy Entecavir | ≤0.10% |
4-Dimethylsilyl Entecavir | ≤0.10% |
Entecavir Related Compone A | ≤0.10% |
Quis non specificatus immunditia | ≤0.10% |
Totalis immunditias | ≤0.30% |
RELICTUM Solvents | |
Methanol | ≤600ppm |
Dichloromethane | ≤300ppm |
Ethyl Acetate | ≤1000ppm |
Tetrahydrofuran | ≤720ppm |
Toluene | ≤890ppm |
Benzyl Chloride | ≤1000ppm |
Benzyl Sin | ≤1000ppm |
Microbial Limit | |
Summa Aerobic Comites | ≤100cfu/g* |
Fermenta et Molds | ≤10cfu/g* |
Mus | Si non Results |
Metalla gravis | ≤10ppm |
Assay | 98.0% ~ 102.0% (HPLC; in anhydrous basis) |
Magnitudo particula | XCV% particularum sit intra 125um |
Test Standard | Enterprise Latin;Pharmacopoeia Civitatum Foederatarum (USP) Standard |
Consuetudinem | Medicamentum antivirale in curatione Hepatitis B infectio |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
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Entecavir Monohydratorum (CAS 209216-23-9) est medicamentum antivirale orale adhibitum in curatione infectio virium Hepatitis B (HBV) .Entecavir Monohydratus est nucleosidum analogum (proprie, analogum guaninum) quae transcriptionem transpositionem vetat, DNA replicationem et transcriptionem in vira.Novum genus est acyl guanosini anti-Hepatitis B virus medicinae cum effectibus pharmacologicis sicut Entecavir.Applicatur amet ad curationem Hepatitis adulti Chronici B in qua est replicatio viralis activa, aucta serum transaminase ALT vel laesiones activas ex histologia hepatis ostendit.Entecavir Monohydratorum potens et selectivus inhibitor HBV est, cum EC50 3.75 nM in cellam HepG2.Entecavir res adversae transcriptase inhibitor est.Hepatitis B Virus (HBV) impedit ne quantitatem virium in corpore multiplicando et minuat.
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