Erlotinib Hydrochloridis CAS 183319-69-9 Puritas >99.0% (HPLC)
Ducens fabrica et supplementum de Hydrochloride Erlotinib intermedia
Erlotinib Hydrochloridis CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxydorum) -3H-Quinazolin-4-unum CAS 179688-29-0
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Nomen chemicum | Erlotinib Hydrochloride |
Synonyma | Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis(2-methoxyethoxydum)-4-(3-ethynylanilinum)quinazolinum hydrochloridum;N-(3-Ethynylphe nyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine HCl |
CAS Number | 183319-69-9 |
CATTUS Number | RF-PI2242 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C22H24ClN3O4 |
M. Pondus | 429.90 |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White Crystalline pulveris |
Lepidium sativum | A: IR: secundum Imaginem Reference B: HPLC: secundum quod referat RT |
Solubilitas | Leviter solutum in aqua, modice solubile in Methanolo et insolubile in Acetonitrile, Acetone, Ethyl, Acetate et Hexane. |
Liquescens punctum | 223.0~229.0℃ |
Damnum in Siccatio | <0.50% |
Residere in Ignition | <0.20% |
Metalla gravis | <20ppm |
una immunditia | <0.50% |
Totalis immunditias | <1.00% |
RELICTUM Solvents | |
Pyridine | <4000ppm |
Chloroform | <4000ppm |
DMF | <3000ppm |
Puritas / Analysis Methodus | >99.0% |
Asssay / Analysis Methodo | 98.5%~ 101.0% (Caculated on Anhydrous Basis) |
Test Standard | Enterprise Standard |
Consuetudinem | API |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore
Hydrochloridis Erlotinib (CAS: 183319-69-9) est parva molecula incrementi epidermalis receptoris tyrosini kinasi convertibilis inhibitoris receptantis, in curatione locali provectae vel metastaticae non parvae cellae cancri et secundae lineae vel tres lineae curationis cancer pancreatis.Erlotinib Hydrochloride probata mense Novembri, 2004, ad curationem cancri pulmonis non-minutae metastaticae provectus est.Eiusdem generis est cum Gefitinib, alterum quinazolinum probatum ad curationem cancri pulmonis provectae, sed cum melioribus proprietatibus pharmacokineticis.Moleculum a Pfizer ortum est et progressum in cooperatione cum OSI initiatum est, quod pleno iure medicamento cum Pfizer cum Warner Lambert immiscuit.Postmodum, Genentech/Roche consensum licentiae iniit cum OSI ad explicandum et mercatum medicatum in Civitates Foederatarum et Mundi.Inhibitoris epidermalis incrementi selectivi factor (EGFR) -tyrosinus inhibitor kinasus.Antineoplastic.Hydrochloridis Erlotinib est HER1/EGFR inhibitor cum IC50 2 nm.Erlotinib HCl praesto est ut 25-, 100-, et 150-mg tabulae fororalis administratio.