Fondaparinux Sodium CAS 114870-03-0 API
Copia cum summa puritate et stabulo Quality
Chemical Name: Fondaparinux Sodium
CAS: 114870-03-0
Antithromboticum Anticoagulantis Factor Xa Inhibitor
API High Quality, Commercial Production
Nomen chemicum | Fondaparinux Sodium |
CAS Number | 114870-03-0 |
CATTUS Number | RF-API84 |
Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
Formulae hypotheticae | C31H43N3O49S8.10Na |
M. Pondus | 1728.08 |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White pulveris |
Asssay / Analysis Methodo | 95.0%~ 103.0% (ex exaruit basis) |
Solubilitas | Solutum in aqua, 2.0M Sodium Chloride et 0.5M Sodium Hydroxide et Insolubile in Ethanol. |
Lepidium sativum 13C-NMR | Resonantiae pro Fondaparinux Sodium observandae sunt 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, 176.7 et 178.0ppm.Mutationes chemicae harum significationum non plus quam ±0.3ppm alia signa altitudines variabiles et chemicae tralationes differunt, quae Sodium Fondaparinux attribuuntur, videri potest inter 58.0~80.5 ppm et 98.7~ 104.5ppm. |
Lepidium sativum HPLC | Retentionis tempus solutionis maioris partis exempli solutionis correspondet solutioni normae |
Lepidium sativum ASS | Natrium proprium habere debet effusio in 330,2nm sub determinatione sodium . |
pH | 6.0~8.0 |
Natrium (Na) | 11.5% ~ 15.0% (Ratio in anhydrous et menstrua libera) |
Free Sulfate | ≤0.30% |
Residua Chloride | ≤1.00% |
Substantiae cognatae | |
immunditiam A | ≤0.80% |
impudicitia B | ≤0.60% |
Una alia immunditia | ≤0.30% |
Totalis immunditias | ≤2.00% |
RELICTUM Solvents | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
DMF | ≤880ppm |
Methylbenzene | ≤890ppm |
Pyridine | ≤50ppm |
Aqua Content (KF) | ≤15.0% |
Bacterial Endotoxins | ≤3.3EU/mg |
Microbial Limit | Numerus Microorganismorum ≤100cfu/g* |
Test Standard | Enterprise Latin;Pharmacopoeia Civitatum Foederatarum (USP) Standard |
Consuetudinem | API, Antithromboticum Anticoagulans, Factor Xa Inhibitor |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
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Fondaparinux Sodium (CAS 114870-03-0) primum est novae classis antithromboticae anticoagulantis chemicae ad grave pondus heparins hypotheticum (LMWH).Fondaparinux sodium factor Xa inhibitor est ad formandum locum altum coniunctionis ligaminis pro factor antithrombin III anti- coagulantis (ATIII).Fondaparinux sodium ligans in hoc situ potentiat effectum inhibitorium naturalem ATIII contra factorem Xa per factorem circiter 300, quod sequitur in inhibitione generationis thrombini.Venales ab GlaxoSmithKline.Versio generica ab Alchemia evoluta in US laboratoria a Dr. Reddy venale est.Fondaparinux sodium primum in US introductum est pro prophylaxi venae profundae thrombosis quae ad embolismum pulmonarium sequentem maiorem chirurgicam orthopaedicam ducere potest.Hoc totum moleculum syntheticum exemplar est seriei heparin pentasaccharidis, fragmentum brevissimum quod catalyze antithrombin lllmediatum inhibitionis factoris Xa inhibet thrombin generationis sine actione antithrombin.
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