Imatinib Mesylate CAS 220127-57-1 Assay 98.0%~ 102.0% Ph+CML API Factory Quality
Commercial Supple Imatinib Mesylate et intermedia:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl) -4-(pyridin-3-yl) pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS:
4-[(4-Methylpiperazin-1-yl) methyl] acidum benzoicum dihydrochloridum CAS: 106261-49-8
| Nomen chemicum | Imatinib Mesylate (forma alpha) |
| Synonyma | Imatinib Methanesulfonate;STI571 Mesylate;CGP-57148B |
| CAS Number | 220127-57-1 |
| CATTUS Number | RF-API19 |
| Stock Status | In Stock, Productio Ascendite ad Tons |
| Formulae hypotheticae | C30H35N7O4S |
| M. Pondus | 589.71 |
| Shipping Condition | Sub Ambient Temperature |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Aspectus | Alba ad Off-White Crystalline pulveris |
| Solubilitas | Facile dissolvere aquam |
| HPLC Lepidium sativum | Sample spectrum principale apicem retentionis temporis secundum quod |
| IR Lepidium sativum | Infrared effusio spectrum specimen secundum quod specimen |
| Liquescens punctum | 214.0~222.0℃ |
| Damnum in Siccatio | ≤0.50% |
| Residere in Ignition | ≤0.10% |
| Metalla gravis | ≤20ppm |
| Substantiae cognatae | (1) Impuritas G: NMT 0.3% |
| (2) Impuritas B: NMT 0.3% | |
| (3) Impuritas C: NMT 0.3% | |
| (4) Impuritas D: NMT 0.3% | |
| (5) Impuritas A: NMT 0.3% | |
| (6) Impuritas H: NMT 0.3% | |
| (7) Impuritas F: NMT 0.3% | |
| (8) Impuritas E: NMT 0.3% | |
| (9) Maxima impudicitia: NMT0.1% | |
| RELICTUM Solvents | (1) Ethyl Acetate: NMT 5000ppm |
| (2) Methanol: NMT3000ppm | |
| (3) Dichloromethane: NMT 600ppm | |
| (4) Ethanol: NMT 5000ppm | |
| (5) Toluene: NMT 890ppm | |
| (6) Dimethyl Sulfoxide: NMT5000ppm | |
| HPLC Assay | 98.0%~ 102.0% (C30H35N7SO4 Calculatum super Basis Anhydrous) |
| Test Standard | Enterprise Standard |
| Consuetudinem | API;Ph+CML |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
Imatinib Mesylate (CAS 220127-57-1) est molecula parva quae kinasum tyrosinum interdum-Abl vetat, kinasum speciei momenti ad multiplicationem myelogenae leukemia longae (CML).Maxime specifica pro BCR-ABL, enzyme cum myelogeno leukemia chronico (CML) et quibusdam formis lymphoblasticis leukemia acutis (ALL).Inhibitor inhibitor potens et selectivus v-Abl tyrosinus est (IC50 = 38 nM).Eventus translocatio inter chromosomata 9 et 22 chromosomatum Philadelphiae gignit, quod inde fusionem interdum Bcr-Abl producit cum actione kinasi aberrantis quae celerem cellulam multiplicationem promovet.Imatinib mesylate ligat hanc kinasem crucialem, claudicans CML incrementum affinis.Imatinib mesylate inhibere PDGFR et kinases tyrosinas cum c-Kit, ulterius inhibere monstratum est.
![4-[(4-Methylpiperazin-1-yl) methyl]acidi dihydrochloridi benzoici CAS 106261-49-8 Imatinib Mesylate intermedia High Munditia](https://www.ruifuchemical.com/uploads/d1fa2a19-300x300.jpg)