Irinotecan Hydrochloridum CAS 100286-90-6 Munditia ≥99.0% (HPLC) API USP Standard Munditia
Manufacturer Supple Irinotecan ac intermedia:
Irinotecan hydrochloridum CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloridis Trihydratorum CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecinum CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidium hydrochloridum CAS: 143254-82-4
| Nomen chemicum | Irinotecan hydrochloride |
| Synonyma | Camptothecin II;CPT-II |
| CAS Number | 100286-90-6 |
| CATTUS Number | RF-API50 |
| Stock Status | In Stock, Productio Ascendite ad Tons |
| Formulae hypotheticae | C33H39ClN4O6 |
| M. Pondus | 623.15 |
| Liquescens punctum | 250-256 (dec.). |
| Repono Conditions | Sub Ambient Temperature |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Aspectus | Alba vel Off-White pulveris |
| Solubilitas | Solutum in aqua et methanolo, in chloroformi, ethanol |
| Lepidium sativum IR | Effusio ultrarubri spectri specimen probati congruere debet cum signis relationis |
| Lepidium sativum HPLC | Retentio temporis maioris apicem solutionis sample debet respondere ad vexillum referentis. |
| Lepidium sativum | Reactionem Chloride Positiva probatio occurrit |
| Humor (KF) | 7.0%~9.0% w/w |
| Residere in Ignition | ≤0.10% |
| Metalla gravis | ≤20ppm |
| Irinotecan Hydrochloride Enantiomer | ≤0.10% (HPLC) |
| 7-Desethyl Irinotecan | ≤0.15% |
| Irinotecan Related Compone A | ≤0.15% |
| 11-Ethyl Irinotecan | ≤0.15% |
| Camptothecin | ≤0.15% |
| Irinotecan Related Compone B | ≤0.15% |
| 7-Ethylcanptothecin | ≤0.15% |
| 7,11-Diethyl-10-Hydroxy Camptothecin | ≤0.15% |
| Quis non specificatus immunditia | ≤0.10% |
| Totalis immunditias | ≤0.50% |
| RELICTUM Solvents (GC) | |
| Methanol | ≤2000ppm |
| Acetone | ≤2000ppm |
| Dichloromethane | ≤500ppm |
| Peteoleum Aether; | ≤100ppm |
| Ethyl Acetate | ≤2000ppm |
| Benzene | ≤2ppm |
| Bacterial Endotoxins | ≤0.29 EU/mg Irinotecan |
| Microbial limites | Totalis comitis Aerobic Microbial: <1000 cfu/g |
| Fingit et Yeasts | <100 cfu/g |
| Puritas / Analysis Methodus | ≥99.0% (HPLC, basis anhydrous) |
| Test Standard | Pharmacopeia Civitatum Foederatarum (USP) Standard |
| Consuetudinem | Active Pharmaceutical Ingredient (API) |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
lrinotecan hydrochloridum (CAS 100286-90-6), semi-syntheticum, aqua solutum derivativum potentis anticancri camptothecin agentis, in Iaponia deductum est ad curationem pulmonis, ovarii et carcinomata ceruicis.lrinotecan suam actionem antitumorem exercet per inhibitionem topoisomerasi I, enzyme celluloso, quod involvitur ad conservandam structuram topographicam DNA in processu translationis, transcriptionis et mitosis.lrinotecan subit de-esterificationem in vivo cedere metabolite activo, SN 38, qui est M-trina potentior quam parens.Deducta therapia irinotecan cum alio agente late adhibito anticancer, cisplatina, relatum est esse superiorem vel soli agenti.lrinotecan in iudiciis clinicis gastrointestinis, pectoris, cutis, colorectalibus, carcinomata pancreatica, mesothelioma et lymphoma non-Hodgkin.
