L-Thyroxine CAS 51-48-9 Puritas >98.0% (HPLC)
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Nomen chemicum | Dominus Thyroxine |
Synonyma | Triticum aestivum;L-T4;NSC 36397;(-)-Thyroxine;3,3',5,5'-Tetraiodo-L-Thyronine;3,5,3',5'-Tetraiodothyronine;beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]alanine;β-((3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl)alanine;o-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine |
CAS Number | 51-48-9 |
CATTUS Number | RF2891 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C15H11I4NO4 |
M. Pondus | 776.87 |
Liquescens punctum | 227.0~230.0℃ |
Ferveret | 576.3±50.0℃ |
Density | 2.635 |
Sensitiva | lux Sensitiva |
Aqua Solubility | Insolubilis in aqua |
Solubilitas | Liquitur in 4M Amonio Hydroxide in Methanolo ad 50mg/ml |
Stabilitas | ≥ 2 Years |
HS Code* | 29379000 |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba vel Off-White Crystalline pulveris |
Puritas / Analysis Methodus | >98.0% (HPLC) |
Liquescens punctum | 227.0~230.0℃ |
Imprimis rotationis [α]20/D | -5.2°~ -6.2° (C=1, Ethanol: 1N NaOH=2:1) |
Metalla gravia (Pb) | ≤10ppm |
Damnum in Siccatio | <0.20% |
Residere in Ignition | <0.10% |
Totalis immunditias | <1.50% |
Infrared Imaginis | Conformat ut Structure |
Test Standard | Enterprise Standard |
Consuetudinem | Pharmaceutical intermedia |
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L-Thyroxine (CAS: 51-48-9) seu Levothyroxinum est thyroidum thyroidum hormone quod chemica idem est cum thyroxino (T4), quod naturaliter est secretus a cellulis follicularibus glandulae thyroideae.Ad hormonum defectus curationi adhibetur, et interdum recursu cancri thyroideae prohibet.Sicut naturaliter secernitur partitio, Levothyroxine est compositio chiralis in L-forma.Medicamentum dextrothyroxinum cognatum (D-Thyroxine) in praeterito adhibitum est ut curatio hypercholesterolemia (celesteria cholesteroli elevata) sed ob effectus cardiacis subtrahitur.L-Thyroxina praecipue adhibetur ad curationem hypothyroidismi, goitis, thyroiditis lymphocytici chronici, myxedema comae et stuporis.In vivo, L-thyroxina (0.9 et 2.7 μg) inhibet synthesim et emissio thyrotropini inducta per thyrotropinum hormona solvens pituitariam anteriorem in muribus.Formulae quae L-Thyroxine continentur in curatione hypothyroidismi adhibitae sunt.Levothyroxina therapia adhibetur in defectu hormonum thyroideae in organismo humano, sicut accidit in defectu glandulae thyroideae, pituitariae et hypothalamicae (respective primariae, secundariae et tertiariae hypothyroidismi).L-Thyroxine etiam in curatione euthyroidis goitidis et goitidis multinodulares adhibetur, inclusis nodulis thyroideae, thyroiditis subacutis vel longis, vel in casu defectus post-chirurgici, vel post curationem radiometabolicam in patientibus cum cancro thyroideo.Effectus huius pharmaci graviter dosis pendent.In parvis dosibus, L-Thyroxinus ostendit actionem anabolicam.In media gustatu excitat incrementum et progressionem textus, metabolismi interdum, pinguium et carbohydratorum, auget activitates functiones systematis nervosi et cardiovascularis centralis, nec non renes et hepatis.In magna dosibus thyrotropicam actionem hypophysis tardat et productionem glandulae thyroidis reprimit.