Lenvatinib Mesylate CAS 857890-39-2 Intende 98.0~ 102.0% Factory
Ruifu Chemical Supple Lenvatinib Mesylate media cum puritate
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylatus CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylatus CAS 205448-66-4
Nomen chemicum | Lenvatinib Mesylate |
Synonyma | 4-[3-Chloro-4-[(cyclopropylaminocarbonyl)amino]phenoxy]-7-Methoxy-6-Quinolinecarboxamide Mesylate;E 7080 Mesylate;Lenvima |
CAS Number | 857890-39-2 |
CATTUS Number | RF-PI1975 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C21H19N4O4Cl.CH4O3S |
M. Pondus | 522.96 |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White vel Crystal |
Lepidium sativum | per IR;per UV;per HPLC |
Solubilitas | Leviter solutum in aqua, prope insolubile in Ethanol |
Liquescens punctum | 228.0~230.0℃ |
Aqua Content (KF) | <1.00% |
Residere in Ignition | <0.10% |
Metalla gravis | <20ppm |
Substantiae cognatae | |
Unam immunditiam | <0.50% |
Totalis immunditias | <1.00% |
Asssay / Analysis Methodo | 98.0~ 102.0% (HPLC Basis in remittit) |
Mole densitas | 0.40gm/ml~0.60gm/ml |
Test Standard | Enterprise Standard |
Consuetudinem | API |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore
Lenvatinib Mesylate (CAS: 857890-39-2) est oralis et multi-iaculator inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, RET cum potentiis antitumoris actionibus.Lenvatinib Mesylate receptaculum tyrosinum kinasum (RTK) inhibitor qui selectivam habet pro VEGFR2.Activitas antineoplasticas exhibet, et aegrorum curationi localiter recurrente vel metastatico, progressivo, iodi radioactivo (RAI) - refracto-refracto differentiato cancri thyroidis indicatus est.Lenvatinib Mesylate primum probatus est ab US Cibus et Drug Administration (FDA) die 13 Feb. 2015, deinde probatus a Pharmaceuticis et Medicis machinis Agency Iaponiae (PMDA) die 26 Mar 2015 probatus est et in Medicina Europaea Agency (EMA) in 28 Maii 2015. Eisai ut Lenvima® amplificata et venales sunt.Lenvatinib Mesylate receptor tyrosinus kinasus inhibitor multiplex oralis est cum singulari ligandi modo, qui selective vetat kinasum actionis incrementi endothelialis vascularium factoris (VEGF) receptorum, praeter alios pathos proangiogenicos et oncogenicos tyrosinos kinases relatas cogitationis implicandas esse in tumore multiplicationis. .Indicatur curatione cancri thyroideae radioiodine-refractariae progressivae differentiatae.Lenvimaper se adhibetur ut cancerem thyroideum differentiatum tractaret (DTC), genus cancri thyroideum, quod iam non potest tractari cum Iodo radioactivo et progreditur.LENVIMA una cum alia medicina, quae everolimus vocatur, adultos tractare cum specie cancri renis, quae carcinoma renum processit (rcc) post unum curationem cum alia medicina anti-cancri.