Letrozole CAS 112809-51-5 API Factory Aromatase Inhibitor II
Copia cum summa puritate et stabulo Quality
Chemical Name: Letrozole
CAS: 112809-51-5
Aromatase Inhibitor II
API High Quality, Commercial Production
Nomen chemicum | Letrozole |
Synonyma | CGS-20267;Femara |
CAS Number | 112809-51-5 |
CATTUS Number | RF-API86 |
Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
Formulae hypotheticae | C17H11N5 |
M. Pondus | 285.3 |
Liquescens punctum | 181.0 ad 183.0℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White Crystalline pulveris |
Solubilitas | Gratis solutum in Dichloromethane, Leviter solutum in Ethanol, et propemodum Insolubile in Aqua. |
Lepidium sativum IR | Spectrum specimen correspondet relationis vexillum |
Lepidium sativum HPLC | Retentio tempus specimen probati correspondet relationis vexillum |
Aqua Content (per KF) | ≤0.30% |
Residere in Ignition | ≤0.10% |
Substantiae cognatae | |
Substantiae cognatae A | ≤0.30% |
Substantiae cognatae B | ≤0.20% |
Quis non specificatus immunditia | ≤0.10% |
Totalis non specificatae immunditias | ≤0.30% |
Totalis immunditias | ≤0.50% |
RELICTUM Solvents | |
Ethyl Acetate | ≤0.50% |
Methanol | ≤0.30% |
Ethanol | ≤0.50% |
DMF | ≤0.088% |
Metalla gravis | ≤10ppm |
Assay | 98.0% ~ 102.0% (ex anhydrous basis ) |
Fasciae vita | XXIV Menses |
Test Standard | Enterprise Standard |
Consuetudinem | API, Aromatase Inhibitor II |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
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Letrozole (CAS 112809-51-5) pars est novae generationis inhibitores valde selectivi aromatasi et est artificialis derivatio benzotriazolis.Letrozole aromatasi inhibet ad gradus inferiores estrogen, ita praeveniens estrogen a tumore augmenti excitando.Eius actio vivo in 150-250 temporibus fortior est quam aromatase primae generationis inhibitor Amarante.Ut valde selectivum, functiones glucocorticoidas, mineralocorticoides et thyroideae non incursum;etiam ad alta dosages, non habebit effectus inhibentes in secretione corticosteroidei adrenalis, dans ei magno tractandi indice.Letrozolus nullam latentem toxicitatem in omnibus systematibus corporeis et organis scopo habet, nullos habet mutagenitos effectus et carcinogenicos, effectus lateris toxici minimos habet, toleratur, et effectus anticancer validiores habet quam inhibitores et antiestrogen medicamenta alia.Letrozole aptum est ad cancer carcinomate pectoris postmenopausali aegros provectos qui non responderit ad curationem estrogen-exprimendam et ad curationem cancri primi pectoris.Solet aegros postmenopausales cum carcinomate provectioris tractare et secundae lineae curationi curationem antiestrogen infeliciter sequi.