Lopinavir CAS 192725-17-0 API Anti-HIV HIV Protease Inhibitor COVID-19 High Munditia
Manufacturer Supple cum High puritate et stabulo Quality
Nomen chemicum: Lopinavir
CAS: 192725-17-0
Potentissima, selectiva Peptidomimetica HIV-1 Protease Inhibitor
COVID-19 Related Research Product
API High Quality, Commercial Production
Nomen chemicum | Lopinavir |
Synonyma | LPV;ABT-378;Kaletra |
CAS Number | 192725-17-0 |
CATTUS Number | RF-API73 |
Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
Formulae hypotheticae | C37H48N4O5 |
M. Pondus | 628.81 |
Long-Term PRAECLUSIO | Copia Diu terminus in 2-8℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White pulveris |
Solubilitas | Sponte solutum in Methanol et Ethanol, solutum in 2-Propanol |
Lepidium sativum IR | Effusio spectri experimenti ultrarubrum concordat cum spectro relationis vexillum |
Lepidium sativum HPLC | Retentio tempus specimen probati correspondet relationis vexillum |
Aqua Content (per KF) | ≤4.0% |
Imprimis Rotatione Optica | -22.0° to -26.0° |
Residere in Ignition | ≤0.20% |
Metalla gravis | ≤20ppm |
Liquescens punctum | 124.0 ad 127.0℃ |
Cinere sulphated | ≤0.20% |
RELICTUM Solvent (Ethanol) | ≤0.50% |
Substantiae cognatae | (HPLC, Area%) |
immunditia 1 | |
Impuritas B (RRT=0.07) | ≤0.20% |
Impuritas I (RRT=1.10) | ≤0.20% |
Alia immunditia | ≤0.10% |
immunditia 2 | Alia individua immunditia ≤0.10% |
Totalis immunditias de modo procedendi I et II " | ≤0.70% |
Totalis immunditias | ≤1.0% |
Temptare (per HPLC) | 98.0%~ 102.0% |
Test Standard | Enterprise Standard |
Consuetudinem | Selective Peptidomimetic HIV-1 Protease Inhibitor, COVID-19 Related Research Product |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
![1](https://www.ruifuchemical.com/uploads/15.jpg)
![](https://www.ruifuchemical.com/uploads/23.jpg)
Lopinavir (ABT-378) valde potens est, inhibitor peptidomimetici selectivi protease HIV-1, cum Kis ex 1.3 ad 3.6 pM pro typo silvestri et protease mutant HIV.Lopinavir actus maturationem HIV-1 comprehendendo ita infectionem suam interclusit.Lopinavir etiam est SARS-CoV 3CLpro inhibitor cum IC50 of 14.2 μM.Lopinavir antiretroviralis classis inhibitoris protease est.Inhibitio HIV-1 protease impedit praecursorem polyprotein viralem et proventus in emissione virionum immaturae, noninfectiosarum.Pars compositionis illic tractandi HIV/AIDS.Lopinavir, sextus HIV protease inhibitor in "navir" classis, in coformulatione cum ritonavir, alius HIV protease inhibitor iam venalis (Abbott, 1996) inmissus est;Haec formula originalis Kaletra introducta est ad usum in compositione cum inhibitoribus vel nucleoside vel non-nucleoside transpositis transcripta pro auxiliis in adultis et pueris curandis.Lopinavir compositio peptidomimetica est cum nucleo structurali identico cum ritonaviro, in quo coetus terminales, praesertim valine modificati, per modum coniunctionis peptidis introductae sunt.Lopinavir potens est inhibitor competitive HIV-I protease exhibens altam potentialem contra ritonavir-resistentes mutationes.In pluribus speciebus animalis, studia pharmacokinetica cum consociatione lopinavirlritonavir ostendit modestas proprietates lopinavirorum signanter emendari coram ritonaviro, secundum Cmax et durationem actionis.
-
Lopinavir CAS 192725-17-0 API Anti-HIV HIV Prot...
-
Favipiravir CAS 259793-96-9 T-705 Munditia ≥99.0%...
-
Darunavir CAS 206361-99-1 Anti-HIV Puritas ≥99.0...
-
Darunavir Ethanolate CAS 635728-49-3 Munditia ≥99...
-
Atazanavir CAS 198904-31-3 Munditia ≥99.0% API Fa...
-
Atazanavir Sulfate CAS 229975-97-7 Munditia ≥99.0...
-
Abacavir CAS 136470-78-5 Pera 99.0%~101.0% API...
-
Abacavir Sulfate CAS 188062-50-2 Pera 98.0%~10...
-
Tenofovir Alafenamide Hemifumarate TAF CAS 1392...
-
Tenofovir CAS 147127-20-6 Perge 98.0%~ 102.0% AP...