Losartan Potassium CAS 124750-99-8 API Factory Antihypertensive High Munditia
Copia Losartan potassium et intermedia cum High Quality
Losartan Potassium CAS 124750-99-8
2-Butyl-4-Chloro-5-Formylimidazole (BCFI) CAS 83857-96-9
| Nomen chemicum | Losartan Potassium |
| Synonyma | DuP 753;Cozaar;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]imidazole-5-methanolum potassium Sal |
| CAS Number | 124750-99-8 |
| CATTUS Number | RF-API98 |
| Stock Status | In Stock, Productio Ascendite ad Tons |
| Formulae hypotheticae | C22H22ClKN6O |
| M. Pondus | 461.01 |
| Liquescens punctum | 263.0~265.0℃ |
| Solubilitas | Gratis solutum in aqua et in Methanol, Leviter solutum in Acetonitrile. |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Aspectus | Alba aut fere alba Crystallina pulveris |
| Lepidium sativum | Infrared effusio: similia Reference Standard |
| Lepidium sativum B * | Ultraviolet effusio: Similia Reference Standard |
| Test Potassium | Debet esse positiuum |
| Aqua Content (KF) | ≤0.50% |
| Metalla gravis | ≤10ppm |
| Substantiae cognatae (HPLC) | |
| Omnis immunditia | ≤0.20% |
| Totalis immunditias | ≤0.50% |
| RELICTUM Solvents (GC) | |
| Cyclohexane | ≤0.10% |
| Isopropyl Sin | ≤0.20% |
| Temptare / Analysis Methodo | 98.5~ 101.0% (HPLC, calculata anhydrous, libero fundamento solvendo) |
| N-Nitrosodiethylamine | ≤0.177ppm (NDEA) |
| N-Nitrosodimethylamine | ≤0.640ppm (NDMS) |
| Magnitudo particula | XC% minus XXXVIII Microns |
| Fasciae vita | XXIV Menses |
| Test Standard | Enterprise Standard |
| Consuetudinem | API, Angiotensin II, Receptor Antagonistae Antihypertensive |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
Losartan Potassium primum est potentem et selectivum angiotensin non-peptidum II receptoris speciei 1 (AT1) adversario in forum introductum ut antihypertensivum orale semel cottidianum.Contentio quae 50% ligationis angiotensin II (IC50) vetat, est 20 nM.Losartan (40 μM) afficit ISC sed impedit effectum ANGII in ISC.Losartan signanter reducit Ang II cellulam mediatam multiplicationem in cellulis cancer endometrialis.Coniunctio losartan et anti-miR-155 maiorem effectum antiproliferativum significanter comparatum cum unoquoque medicamento solum habet.Metabolized est ad metabolitum acidum 5-carboxylicum producendum (EXP3174) et ad sanguinis pressionem inferiorem refertur.Praesens inquiritur ut curatio potentialis pro COVID-19 pro sua potentia ad indicia COVID-19 mitiganda vel minuenda.
1. Ad curationem hypertensionis essentialis, adhiberi potest sola vel in compositione cum aliis medicamentis antihypertensivis (ut diureticis).2. Ad defectum cordis curationem, adhiberi potest solum vel in compositione cum medicamentis chemicis cardiotonicis vel diureticis.3. Praeveniendi plaga in aegris hypertensione et hypertrophia ventricularis sinistri.4. Ad tardam progressionem nephropathiae in aegris cum diabete typo 2 diabete cum nephropathia et hypertensione coniungitur.
