Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-22-8 Puritas >99.0% (HPLC) Nintedanib Esylate Factory intermedia
Shanghai Ruifu Chemical Co., Ltd. est primarius fabricae et supplementi Methyl 2-Oxoindolini-6-Carboxylati (CAS: 14192-26-8) magna cum qualitate, productio commercialis.
Nomen chemicum | Methyl 2-Oxoindoline-6-Carboxylatus |
Synonyma | 2-Oxoindoline-6-Carboxylic Acidum Methyl Ester;Methyl Oxindole-6-Carboxylata |
CAS Number | 14192-26-8 |
CATTUS Number | RF-PI1524 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C10H9NO3 |
M. Pondus | 191.19 |
Liquescens punctum | 184.0~190.0℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Lux Yellow ut Brown pulveris |
1 H NMR Spectrum | Congruunt cum Structure |
Puritas / Analysis Methodus | >99.0% (HPLC) |
Damnum in Siccatio | <1.00% |
Totalis immunditias | <1.00% |
Test Standard | Enterprise Standard |
Consuetudinem | Intermedia Nintedanib Esylate (CAS: 656247-18-6) |
Methyl 2-Oxoindoline-6-Carboxylatus (CAS: 14192-22-8) Synthetica Route
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;A luce et humore protege.
Methyl 2-Oxoindoline-6-Carboxylatus (CAS: 14192-26-8) media usus est ad parandum Nintedanib Esylate (CAS: 656247-18-6).Nintedanib Esylate inhibitor angiokinasi triplex potens, oralis a Boehringer Ingelheim evoluta est, qui scopos proangiogenicos et pro-fibroticos per vias endotheliales vasculares mediatas incrementi factoris receptoris, fibroblastae aucti factoris receptoris et aucti factoris receptae familiae, necnon Src et Flt-3 kinases.Nintedanib Esylate probata est pro curatione fibrosis pulmonis idiopathicae (IPF), condicio qua paulatim cicatrices per tempus fiunt, ab US FDA mense Octobre 2014 et ab EMA mense Ianuario 2015. FDA nintedanib esylate ieiunii semita concessit. recensio prioritas, pupillus productus et designationes breakthrough.Hoc etiam ab EMA mense Novembri 2014 probatum est propter curationem cancri cellulae non parvae coniuncte cum docetaxel post primam aciem chemotherapyam.